Minnesota Twins vs Milwaukee Brewers Picks, Prediction, Odds, and Line Movement for Friday August 7 2026

By: Kyle Kargel Published 08/07/2026, 08:35 AM ET
Twins vs Brewers picks

The Minnesota Twins and Milwaukee Brewers open a three-game series Friday night at American Family Field, and this opener is loaded with value for anyone tracking MLB picks and MLB predictions this week. For more selections across the slate, check out these MLB picks before first pitch. Milwaukee enters as a sizable home favorite behind a superior starting pitcher, while Minnesota will be without its top power threat for this matchup. This preview breaks down the odds, the line movement, the starting pitching, and the injuries shaping this series opener.

TLDR: Quick Picks and Prediction

  • Side: Brewers -1.5 (+124)
  • Total: Under 8 (-118)
  • Final Score Prediction: Brewers 5, Twins 2

Odds and Line Movement

Current Odds

Team Moneyline Run Line Total
Minnesota Twins +158 +1.5 (-149) Over 8 (-102)
Milwaukee Brewers -170 -1.5 (+124) Under 8 (-118)

Line Movement - Moneyline

Date Time Minnesota Milwaukee Public ($, #)
08/07 05:33:54AM +158 -170 MIL 94%, 94%
08/07 05:33:54AM +148 -179 MIL 87%, 94%
08/07 02:37:09AM +144 -175 MIL 92%, 92%
08/07 00:44:17AM +144 -175 MIL 91%, 90%
08/07 00:44:17AM +149 -181
08/07 00:37:35AM +153 -186
08/07 00:30:55AM +149 -181
08/07 00:25:26AM +153 -186

Line Movement - Total

Date Time Over Under Public ($, #)
08/07 05:33:54AM 8o-101 8u-120
08/07 04:29:24AM 7œo-117 7œu-103
08/07 02:37:09AM 7œo-119 7œu-101
08/07 00:44:17AM 7œo-118 7œu-102
08/07 00:30:55AM 8o-102 8u-118
08/07 00:25:26AM 8o-105 8u-115

Twins vs Brewers Key Matchups and Game Preview

Zebby Matthews is 4-8 with a 5.22 ERA and 1.31 WHIP across 81 innings, allowing 80 hits and 16 home runs while recording 69 strikeouts against 26 walks, numbers that present a difficult matchup against a Milwaukee club averaging more offensive production than Minnesota. Shane Drohan has been considerably steadier, posting a 6-4 record, 3.48 ERA and 1.17 WHIP through 88 innings with 89 strikeouts, only 24 walks and seven homers allowed.

Brewers Starting Pitching Edge

Milwaukee also owns a substantial season-long pitching advantage with a 3.44 team ERA and 1.16 WHIP compared to Minnesota's 4.62 ERA and 1.38 WHIP. Drohan's ability to limit walks and home runs makes him one of the more reliable arms in this series opener.

Twins Rotation Struggles

Matthews' 16 home runs allowed across just 81 innings is a concerning rate, and his 5.22 ERA suggests Minnesota will need strong offensive support to stay competitive in this matchup.

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Milwaukee Offensive Production

Offensively, the Brewers are batting .253 with a .336 OBP and have scored 571 runs, while the Twins are hitting .243 with a .317 OBP and have scored 539. Jackson Chourio has supplied a .277 average and .470 slugging percentage, and Brice Turang leads Milwaukee with 70 RBI while batting .266.

Twins Missing Byron Buxton

Minnesota does possess more home-run power, 137 to Milwaukee's 106, but its biggest threat, Byron Buxton, is on the 10-day injured list after producing 25 homers, a .263 average and .544 slugging percentage. His absence removes an important middle-of-the-order weapon, placing more pressure on Josh Bell, who has 14 homers and a team-leading 65 RBI.

Brewers Injury Concerns

Milwaukee has injury concerns of its own, with Jake Bauers day-to-day after hitting 20 home runs with 64 RBI, while Sal Frelick remains on the injured list. Those absences add some uncertainty to an otherwise favored Brewers lineup.

Milwaukee's Recent Form

The Brewers enter 72-43 and riding a three-game winning streak, whereas Minnesota is 57-59 after losing four of its last five. Milwaukee also leads the season series 2-1 after taking two of three in Minnesota in May.

  • Milwaukee enters at 72-43 and is riding a three-game winning streak.
  • Minnesota is 57-59 after losing four of its last five games.
  • Milwaukee leads the season series 2-1 after taking two of three meetings in Minnesota back in May.
  • The Brewers own a significant team pitching advantage over the Twins this season.

MIL vs MIN Key Injuries and Things To Know

Brewers Injury Report

Jake Bauers is day-to-day after hitting 20 home runs with 64 RBI, while Sal Frelick remains on the injured list. Despite those absences, Milwaukee's overall pitching and offensive depth remain strong entering this series.

Twins Injury Report

Byron Buxton is on the 10-day injured list after producing 25 homers, a .263 average and .544 slugging percentage this season. His absence removes Minnesota's most explosive bat from the middle of the lineup for this matchup.

Twins vs Brewers Side and Over/Under Picks

Brewers Run Line Pick

  • Pick: Brewers -1.5 (+124)
  • Drohan's superior run prevention, Milwaukee's excellent staff numbers and Buxton's unavailability all support the Brewers covering the run line at a favorable plus-money price.

Total Pick Breakdown

  • Pick: Under 8 (-118)
  • Drohan has limited both traffic and home runs effectively, while Minnesota's lineup loses considerable explosiveness without Buxton, supporting the under in this series opener.

Final Score Prediction

  • Projected Score: Brewers 5, Twins 2
  • Drohan controls the game against a Buxton-less Minnesota lineup, while Milwaukee's offense, led by Chourio and Turang, does enough against Matthews to open the series with a win.

How to Wager On Twins vs Brewers

For this Twins vs Brewers matchup, the clearest value sits with the Milwaukee run line and the under, given Drohan's command edge and the absence of Byron Buxton from the Minnesota lineup. Bettors looking to sharpen their approach further can also explore additional resources, including AI picks for data-driven projections, the Dimers review for a closer look at model-based predictions, and the Oddible review for another angle on odds and line tracking before finalizing a wager on this matchup.

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