Minnesota Twins vs New York Mets Picks and Predictions for Tuesday April 21 2026

By: Kim Smith Published 04/21/2026, 01:00 AM ET
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The Minnesota Twins head to Citi Field to take on the New York Mets in Queens, New York, on Tuesday, April 21, 2026. First pitch is scheduled for 7:10 PM ET with coverage available on MLB.TV. At the time of this writing the odds were not released. Both teams enter this matchup looking to turn recent struggles into a more positive stretch, which sets up an interesting contest between two clubs trying to regain momentum. Be sure to check out free MLB picks before placing any wagers.

Starting Pitchers Matchup

Simeon Woods Richardson takes the ball for Minnesota with a 0-3 record, carrying a 6.10 ERA and a 1.60 WHIP across 20.2 innings pitched. He has allowed 26 hits while striking out 11 and walking seven, showing some difficulty limiting contact early in the season. On the other side, Nolan McLean gets the start for New York with a 1-1 record, posting a strong 2.28 ERA and an impressive 0.76 WHIP over 23.2 innings. He has allowed just 10 hits while striking out 28 and issuing eight walks, demonstrating strong command and the ability to miss bats.

Minnesota Searching for Answers on the Road

Minnesota enters this matchup with an 11-11 overall record and has struggled away from home, posting a 4-5 record on the road. Their recent stretch has been difficult, as they have recently lost multiple games to Cincinnati and also dropped several contests to Boston, with their only recent win coming in a shutout victory over Boston. This run highlights inconsistency and challenges in both scoring and closing out games.

Offensively, Minnesota is hitting .230 as a team with 112 runs scored and 166 hits. They have hit 26 home runs while maintaining a .332 on-base percentage and a .381 slugging percentage. On the pitching side, they carry a 4.06 ERA with a 1.37 WHIP, while opponents are hitting .253 against them.

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The key weakness for Minnesota has been their pitching consistency, as the higher WHIP and opponent batting average suggest difficulty in limiting base runners. This has made it challenging to control games, especially during their recent losing stretch.

New York Looking to Reverse Recent Results

New York comes into this game with a 7-15 overall record and has gone 3-6 at home this season. Their recent performance has been challenging, as they have recently lost multiple games to Chicago and also dropped games to Los Angeles, showing difficulty finding consistent success over their last several outings.

Offensively, New York is hitting .226 with 72 runs scored and 169 hits. They have hit 16 home runs while carrying a .288 on-base percentage and a .336 slugging percentage. Their pitching has been comparable to Minnesota, posting a 4.06 ERA with a 1.28 WHIP while limiting opponents to a .239 batting average.

The most notable strength for New York is their ability to limit hits, as the .239 opponent batting average indicates a pitching staff that can control contact better than their opponent. This has helped keep games within reach despite their recent struggles.

Minnesota Twins vs New York Mets Picks and Prediction

Minnesota Twins vs New York Mets Pick

Pick: New York Mets Moneyline

New York holds the edge in this matchup due to stronger starting pitching and slightly better control on the mound overall. Nolan McLeanโ€™s early performance stands out, particularly with his ability to limit hits and generate strikeouts. While both teams have struggled recently, New Yorkโ€™s pitching advantage provides a solid foundation to build on in this game.

Minnesota Twins vs New York Mets Total Pick

Pick: Under

Iโ€™m leaning toward the under in this matchup because both teams have shown inconsistent offensive production, and New Yorkโ€™s pitching has been effective at limiting hits. Minnesotaโ€™s struggles on the mound could create some scoring chances, but overall this sets up as a game that may stay on the lower side.

Final Score Prediction: New York Mets 4 โ€“ Minnesota Twins 3

This prediction was written before the completion of game play on Monday.

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