Minnesota Twins vs Pittsburgh Pirates Picks and Prediction for Friday May 29 2026

By: Eddie Kline Published 05/29/2026, 01:40 AM ET

Twins Preview

Scenic PNC Park will play host to a Friday night MLB interleague clash between the Minnesota Twins and the Pittsburgh Pirates. Be ready for the baseball season with all of our MLB predictions. The Twins (27-30) have won seven of their last 11 games and are five games out of first place in the AL Central Division standings. On Thursday, Minnesota batters went 0-for-6 with runners in scoring position and left six men on base during a 6-2 road loss against Chicago.

Twenty-five year old righty Taj Bradley (5-1 2.77 ERA) is flourishing in his first season with the Twins. Last time out, Bradley (5 IP) allowed one run and retired seven batters by strikes during a 4-2 road victory against Boston.

Pirates Preview

The Pittsburgh Pirates have split their first 30 home games and are trying to climb out of the NL Central Division cellar. Last night, Pittsburgh committed a pair of errors and DH Bryan Reynolds went 2-for-3 with a home run during a 7-2 home loss versus Chicago. SP Paul Skenes (6-5) struck out ten batters in five plus innings and was the hard luck loser for the Pirates, who fell to 29-28 overall.

The Pirates will counter with thirty year old right-hander Mitch Keller (5-2 3.64 ERA) in the series opener. In his last start, Keller (6 IP) limited Toronto to one run and fanned five batters during a 4-1 road victory.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Twins vs Pirates Pick

Minnesota C Ryan Jeffers had surgery on his fractured left hamate bone and will miss the next 6-to-8 weeks. Through 57 games, Minnesota ranks 14th in OPS and 8th in runs scored. For the season, Pittsburgh ranks 8th in OPS and 5th in runs scored. Take the Pirates to win at home. Final Score Prediction, Pittsburgh Pirates win 5-3.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $150 in Bonus Bets *Paid Within 14 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Cashable No
Video: Wednesday MLB Picks Today | MLB Predictions, Props & Best Bets | Morning Wager 7/29
Wednesday MLB Picks Today | MLB Predictions, Props & Best Bets | Morning Wager 7/29
Video: Cubs vs Cardinals: MLB Best Bets TODAY! | Best MLB Picks July 29, 2026
Cubs vs Cardinals: MLB Best Bets TODAY! | Best MLB Picks July 29, 2026
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.