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Minnesota Twins vs Pittsburgh Pirates Picks and Prediction for Friday May 29 2026

By: Eddie Kline Published 05/29/2026, 01:40 AM ET

Twins Preview

Scenic PNC Park will play host to a Friday night MLB interleague clash between the Minnesota Twins and the Pittsburgh Pirates. Be ready for the baseball season with all of our MLB predictions. The Twins (27-30) have won seven of their last 11 games and are five games out of first place in the AL Central Division standings. On Thursday, Minnesota batters went 0-for-6 with runners in scoring position and left six men on base during a 6-2 road loss against Chicago.

Twenty-five year old righty Taj Bradley (5-1 2.77 ERA) is flourishing in his first season with the Twins. Last time out, Bradley (5 IP) allowed one run and retired seven batters by strikes during a 4-2 road victory against Boston.

Pirates Preview

The Pittsburgh Pirates have split their first 30 home games and are trying to climb out of the NL Central Division cellar. Last night, Pittsburgh committed a pair of errors and DH Bryan Reynolds went 2-for-3 with a home run during a 7-2 home loss versus Chicago. SP Paul Skenes (6-5) struck out ten batters in five plus innings and was the hard luck loser for the Pirates, who fell to 29-28 overall.

The Pirates will counter with thirty year old right-hander Mitch Keller (5-2 3.64 ERA) in the series opener. In his last start, Keller (6 IP) limited Toronto to one run and fanned five batters during a 4-1 road victory.

Twins vs Pirates Pick

Minnesota C Ryan Jeffers had surgery on his fractured left hamate bone and will miss the next 6-to-8 weeks. Through 57 games, Minnesota ranks 14th in OPS and 8th in runs scored. For the season, Pittsburgh ranks 8th in OPS and 5th in runs scored. Take the Pirates to win at home. Final Score Prediction, Pittsburgh Pirates win 5-3.

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