MLB Player Props for Wednesday, September 10 2025

By: Devin Erickson-Sheehy Updated 09/10/2025, 02:20 PM ET
Use Code PPWC

The Wednesday night MLB slate is loaded with value on the prop betting market, and we’ve zeroed in on three spots that stand out.

From strikeout fades to a superstar slugger with a strong history against tonight’s opposing starter, these are our favorite MLB props for September 10.

Check out our MLB picks for every matchup tonight including picks on sides and totals for every game.

Today’s MLB Prop Picks

  • Jake Irvin under 3.5 strikeouts (-135)

    Sign Up Get $30 Premium Picks Credit + Exclusive Offers

    Subscribe Now

    I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.
  • Jack Flaherty under 14.5 outs recorded (+120)

  • Shohei Ohtani over 2.5 total bases (-105)

Jake Irvin Under 3.5 Strikeouts

We were on this same prop last Friday, and the logic still holds.

Irvin’s strikeout rate has cratered since August, and he simply isn’t fooling hitters at all. Now he matches up with a Miami Marlins lineup that ranks fifth in baseball in lowest strikeout rate, making them one of the toughest teams to punch out.

The Fish put the ball in play consistently, and given Irvin’s diminished whiff rate, it’s hard to envision him reaching four strikeouts tonight.

See also: Nationals vs Marlins pick

Jack Flaherty Under 14.5 Outs Recorded

Flaherty has struggled on the road all season, carrying a bloated 5.64 ERA away from home. Yankee Stadium is not the place to expect him to turn things around, especially against a New York lineup that thrives in the Bronx.

The Yankees’ patience at the plate has also been a problem for pitchers like Flaherty who walk batters at an above-average rate. We don’t see him making it through five innings here, making the under on 14.5 outs a strong play.

See also: Tigers vs Yankees pick.

Shohei Ohtani Over 2.5 Total Bases

When a superstar like Ohtani has owned a particular pitcher, it’s worth backing. Against Rockies left-hander Kyle Freeland, Ohtani has gone 6 for 8 with two home runs in his career. That kind of dominance, albeit in a limited sample, underscores the matchup advantage he enjoys tonight.

Whether it’s via a gap shot, a double down the line, or another blast into the seats, Ohtani has multiple paths to clear this 2.5 total bases prop and cash another ticket for bettors.

See also: Rockies vs Dodgers pick. 

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $200 in Bonuses Instantly!

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Odds Requirements -500
Cashable No
Video: World Cup: Mexico vs England BEST Bets & Predictions | July 5, 2026
World Cup: Mexico vs England BEST Bets & Predictions | July 5, 2026
Video: Brazil vs Norway: The Bet You AREN'T Thinking Of! | BEST World Cup Predictions | July 5, 2026
Brazil vs Norway: The Bet You AREN'T Thinking Of! | BEST World Cup Predictions | July 5, 2026
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.