New York Mets vs Cleveland Guardians Picks and Prediction for Tuesday August 4 2026
Mets Preview
In Tuesday night MLB interleague action, the New York Mets will travel to Progressive Field to take on the Cleveland Guardians. Be ready for the baseball season with all of our MLB predictions. The Mets (47-66) have dropped 32 of their first 54 road games and own the second worst overall record in the National League. New York spent Monday’s trade deadline selling much of their high-leverage bullpen arms. On Sunday, New York went 0-for-12 with runners in scoring position during a 2-0 home loss versus Miami.
Thirty-four year old southpaw Sean Manaea (4.42 ERA) will make his tenth start of the season for the Mets. Last time out, Manaea (6 IP) allowed five hits and a pair of runs during a 3-2 home victory versus Atlanta. Through 91 plus innings, Manaea has retired 88 batters by strikes.
Guardians Preview
While the Mets are the highest spending team in baseball, the Cleveland Guardians entered the 2026 MLB season with the lowest payroll. The Guardians (57-56) have split their first 56 home games and are three games back of Chicago for the top spot in the AL Central Division. On Sunday, Cleveland OF Chase DeLauter went 2-for-4 with three RBIs to spark Cleveland to a 5-0 home victory versus Arizona.
The Guardians will counter with twenty-six year old righty Joey Cantillo (8-6 3.88 ERA) on Tuesday. In his last start, Cantillo fired four shutout frames and fanned eight batters to lead Cleveland to a 6-1 road victory against Cincinnati.
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Mets vs Guardians Pick
New York OF Juan Soto has landed on the 10-day injured list with a strained left calf and will not play in this series. Through 113 games, New York ranks 28th in OPS and 27th in runs scored. For the season, Cleveland ranks 30th in OPS and 29th in runs scored. Take the Guardians to win at home. Final Score Prediction, Cleveland Guardians win 5-2.
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