New York Yankees vs Baltimore Orioles Picks and Prediction for Friday September 19 2025

By: Eddie Kline Published 09/19/2025, 12:50 AM ET
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AL East Division rivals will square off on Friday night, when the New York Yankees take on the Baltimore Orioles from Camden Yards. Be ready for the baseball season with all of our MLB predictions.

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Game Details For Yankees vs Orioles

  • September 19th, 2025
  • 7:05 pm EST
  • Camden Yards
  • TV MASN

Yankees Spotlight Player

  • Two-time American League MVP Aaron Judge leads the majors with a .329 batting average. Judge also ranks in the top ten in home runs (48) and RBIs (103). Judge came very close to winning the triple crown in 2022 and could do it at some point in his career.

Yankees Supporting Cast & Depth

  • Twenty-six year old righty Will Warren (8-7 4.44 ERA) will be on the bump for the Yankees. Warren ranks 32nd in the majors with 160 strikeouts and has fanned 11 Baltimore batters across nine plus frames.

Orioles Spotlight Player

  • Twenty-seven year old southpaw Trevor Rogers (8-2 1.43 ERA) has been a major reason for Baltimore’s second-half turnaround. Over his previous five starts, Rogers (31.1 IP) has limited the opposition to six runs (5 ER) and retired 33 batters by strikes.

Orioles Supporting Cast & Depth

  • SS Gunnar Henderson has been hot for the Orioles at the plate. Over his past five games, Henderson has collected eight hits and scored three runs.
  • Baltimore’s bullpen has been problematic all season long, ranking near the bottom of the American League with a 4.59 ERA and converting 37 of 57 save opportunities.

Betting Line Breakdown

  • NYY -120 ; Total 9
  • Baltimore has been money with Rogers on the mound. The Orioles have won eight of his last ten starts and he would be the Cy Young Award winner if he pitched the entire season.

Picks For Yankees vs Orioles

  • Trevor Rogers under 2.5 runs
  • Trevor Rogers over 4.5 strikeouts
  • Gunnar Henderson over 1.5 hits + runs + RBIs
  • Aaron Judge over 1.5 hits + runs + RBIs
  • Will Warren over 4.5 strikeouts
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