New York Yankees vs Boston Red Sox Picks and Predictions for Thursday April 23 2026

By: Kim Smith Published 04/23/2026, 01:00 AM ET
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The New York Yankees travel to Fenway Park in Boston, Massachusetts to take on the Boston Red Sox on Thursday, April 23, 2026, with first pitch scheduled for 6:10 PM and coverage available on MLB.TV, FOX, and FS1. At the time of this writing the odds were not released. This matchup features a Yankees team that has been performing well on the road against a Red Sox team looking to find consistency at home. Be sure to check out free MLB picksย for more daily insights.

Starting Pitchers Overview

Cam Schlittler will start for New York, entering with a 2-1 record, a 1.95 ERA, and a 0.76 WHIP across 27.2 innings. He has allowed 18 hits while striking out 36 batters and issuing just three walks, showing strong command and efficiency. On the other side, Brayan Bello takes the mound for Boston, holding a 1-2 record with a 6.75 ERA and a 1.93 WHIP over 18.2 innings. He has given up 24 hits while recording 13 strikeouts and 12 walks, indicating more difficulty in limiting baserunners.

Yankees Carrying Strong Form Into Boston

New York enters this contest with a 14-9 overall record and a 6-4 mark on the road. Over their last five games, the Yankees have recently won over Boston and Kansas City multiple times, while suffering one loss to Los Angeles. That stretch highlights a team that has been playing with confidence and consistency in recent matchups.

From a statistical perspective, New York has posted a .222 batting average with 114 runs and 165 hits. Their offense has delivered 33 home runs, supported by a .326 on-base percentage and a .411 slugging percentage. On the pitching side, the Yankees have recorded a 3.25 ERA and a 1.15 WHIP, while holding opponents to a .225 batting average.

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A key strength for New York is their pitching efficiency, as their 3.25 ERA and .225 opponent batting average show their ability to limit scoring opportunities. That consistency on the mound has been a major factor in their recent success.

Boston Searching for Stability at Home

Boston comes into this matchup with a 9-14 overall record and a 5-6 mark at home. In their last five games, the Red Sox have recently lost to New York but also picked up a win over Detroit, while suffering losses to Detroit multiple times as well. That recent stretch reflects a team that has struggled to maintain consistent results.

Looking at the numbers, Boston has posted a .229 batting average with 89 runs and 175 hits. They have hit 13 home runs while maintaining a .314 on-base percentage and a .338 slugging percentage. On the pitching side, the Red Sox hold a 4.40 ERA and a 1.34 WHIP, while allowing opponents to hit .243.

A notable weakness for Boston is their offensive production, as their 13 home runs and .338 slugging percentage indicate limited power compared to their opponent. That lack of extra-base production could be a key factor in this matchup.

New York Yankees vs Boston Red Sox Picks and Prediction

New York Yankees vs Boston Red Sox Pick

Pick: New York Yankees Moneyline

New York enters this game with a clear advantage based on pitching performance and recent form. Their lower ERA and WHIP compared to Boston highlight a more efficient pitching staff, while their ability to generate more home runs provides additional offensive support. Bostonโ€™s higher ERA and WHIP suggest challenges in limiting scoring opportunities, which could play into New Yorkโ€™s strengths. With stronger overall metrics and better recent results, the Yankees are positioned well to secure another win.

New York Yankees vs Boston Red Sox Total Pick

Pick: Over 8.5

Both teams have shown the ability to contribute offensively, and Bostonโ€™s pitching numbers suggest that runs could be available in this matchup. While New York has been more effective on the mound, their offensive production combined with Bostonโ€™s struggles creates a scenario where scoring opportunities could build. I expect both teams to find ways to generate runs, making the over a solid option in this contest.

Final Score Prediction: New York Yankees 6 โ€“ Boston Red Sox 3

This prediction was written before the completion of game play on Wednesday.

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