New York Yankees vs Chicago White Sox Picks, Prediction, Odds, and Line Movement for Tuesday July 28 2026

By: Kyle Kargel Published 07/28/2026, 09:38 AM ET
Yankees vs White Sox picks

Tuesday night's MLB predictions slate continues with Game 2 of a four-game series between the New York Yankees and Chicago White Sox at Rate Field, with first pitch scheduled for 7:40 p.m. ET. New York enters at 60-46 after winning Monday's opener 9-5, while Chicago fell to 55-50 but remains atop the American League Central. With the Yankees sitting as favorites and the total set at eight runs, this pitching matchup offers a clear angle for bettors before first pitch.

TLDR: Quick Picks and Prediction

  • Spread Pick: Yankees -1.5 (+123)
  • Total Pick: Under 8
  • Projected Final Score: Yankees 5, White Sox 2

Odds and Line Movement

New York is currently priced at -136 on the moneyline with Chicago available at +113, while the Yankees can also be backed at +123 on the -1.5 run line. The total sits at eight runs. Below is a breakdown of how the numbers and public betting percentages have moved since Sunday afternoon.

Current Odds

Date Time NY Yankees Chi. White Sox Public ($, #)
07/28 08:52:41AM -136 +113 NYY 77%, 80%

Line Movement - Moneyline

Date Time NY Yankees Chi. White Sox Public ($, #)
07/28 08:52:41AM -136 +113 NYY 77%, 80%
07/28 00:09:23AM -135 +112 NYY 77%, 80%
07/28 00:09:23AM -135 +112 NYY 68%, 76%
07/28 00:09:23AM -135 +112 NYY 66%, 77%
07/28 00:09:23AM -135 +112 NYY 68%, 80%
07/27 08:10:29PM -135 +112 CHW 73%, 42%
07/27 08:10:29PM -135 +112 CHW 82%, 33%
07/27 06:36:06PM -137 +114 CHW 82%, 33%
07/27 05:35:37PM -144 +119
07/27 03:39:56PM -144 +119 NYY 93%, 87%
07/27 02:09:24PM -149 +123

Line Movement - Total

Date Time Over Under Public ($, #)
07/28 08:52:41AM 8o-107 8u-112 O91%, U60%
07/27 11:00:48PM 8o-114 8u-105 U93%, O50%
07/27 08:10:29PM 8o-117 8u-103 U91%
07/27 06:36:06PM 8o-118 8u-102
07/27 06:15:55PM 8o-119 8u-102
07/27 06:04:36PM 8o-117 8u-103
07/27 05:35:37PM 8o-119 8u-102
07/27 04:04:47PM 8o-117 8u-103
07/27 03:39:56PM 8o-115 8u-105
07/27 02:46:41PM 8o-111 8u-109
07/27 02:09:24PM 8o-105 8u-115

Yankees vs White Sox Key Matchups and Game Preview

Yankees Pitching Advantage

Gerrit Cole starts for New York with a 3-5 record, 3.92 ERA and excellent 1.10 WHIP through 62 innings this season. Cole has recorded 66 strikeouts against only 12 walks while allowing 56 hits, although his 11 home runs surrendered show that he has not been completely immune to hard contact.

White Sox Rotation Risk

Chicago counters with left-hander Anthony Kay, who is 7-4 with a 4.21 ERA and 1.37 WHIP across 98.1 innings. Kay has allowed 95 hits, 40 walks and 14 home runs while collecting 80 strikeouts, and his control issues could be costly against a patient Yankees lineup.

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New York's Power Numbers

New York is batting only .234, but its power has fueled 497 runs, 152 home runs and a .418 slugging percentage. Ben Rice has carried a heavy offensive load with 31 homers, 73 RBIs, a .275 average, .363 on-base percentage and .585 slugging percentage.

Chicago's Offensive Production

Chicago is batting .241 with 506 runs and 136 home runs, while Sam Antonacci leads the club with a .281 average and .374 on-base percentage. Colson Montgomery has supplied 24 homers and 61 RBIs, while Miguel Vargas owns a team-high 63 RBIs.

Yankees Missing Key Power Bats

The Yankees' lineup remains significantly weakened by injuries to Aaron Judge, Giancarlo Stanton and Cody Bellinger, removing three established power threats from the middle of the order. Judge remains sidelined by a rib injury, Stanton is recovering from a calf strain and Bellinger recently suffered a hamstring strain.

White Sox Bullpen Depth

Chicago is missing Austin Hays, while several relievers, including Jordan Leasure, Tyler Gilbert and Prelander Berroa, remain unavailable, reducing the White Sox's pitching depth.

Public money has favored New York consistently across the last two days, with the share of tickets on the Yankees ranging from 76% to 93% throughout the window. As of the most recent 07/28 update at 08:52:41AM, the market shows 77% of money and 80% of bets on New York. Notably, Chicago drew heavier ticket support Sunday evening, with 82% of money and 33% of bets on the White Sox as of 07/27's 06:36:06PM line, even though the number itself moved in New York's favor from -149 down to -136 by Tuesday morning. On the total, the public has leaned Under recently, with 93% of money on the Under as of 07/27's 11:00:48PM update, while the most current 07/28 line shows 91% of money on the Over.

Key Injuries and Things To Know: NYY and CHW

  • Aaron Judge remains sidelined by a rib injury for New York.
  • Giancarlo Stanton is recovering from a calf strain.
  • Cody Bellinger recently suffered a hamstring strain.
  • Chicago is missing Austin Hays.
  • Relievers Jordan Leasure, Tyler Gilbert and Prelander Berroa remain unavailable for the White Sox.

Yankees vs White Sox Side and Over/Under Picks

Despite those absences, New York demonstrated in the opener that its remaining hitters can still generate offense. Cole offers the Yankees a clear advantage in command and baserunner prevention, while Kay's elevated walk rate creates opportunities for New York to produce runs without relying entirely on home runs. Chicago's offense is capable of keeping the game close, but the starting-pitching edge and stronger overall run-prevention numbers favor the visitors.

  • Side Pick: Yankees -1.5 (+123)
  • Total Pick: Under 8

Final Score Prediction

  • New York Yankees 5, Chicago White Sox 2

How to Wager On Yankees vs White Sox

Bettors weighing New York's run line and the Under in this series matchup have a few resources to compare projections before placing a wager. For a data-driven cross-check on Cole's edge over Kay, exploring AI picks can help validate the command gap between these two starters. Bettors can also review the Dimers review for another projection angle on Yankees vs White Sox, or check the Oddible review for an additional resource to weigh against New York's spread and the Under before locking in a final decision.

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