New York Yankees vs Minnesota Twins Picks and Predictions for Monday, September 15, 2025

By: David Anicetti Published 09/15/2025, 12:00 AM ET
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The New York Yankees and  Minnesota Twins meet Monday evening at Target Field in Minneapolis, with the first pitch scheduled for 7:40 PM ET on MLB.TV. New York enters at 83–65 overall and 39–34 on the road, while Minnesota is 65–83 with a 36–37 home record. Win big with our free MLB Picks.

New York Yankees Preview

New York has won three straight. The Yankees trail first place in the American League East by three games and currently hold the first of three AL Wild Card spots. Carlos Rodon takes the mound with a 16–8 record, 3.11 ERA, and 186 strikeouts in 176.1 innings. He has held hitters to a .231 average and matches up well against a Twins lineup that ranks among the league leaders in strikeouts. The Yankees’ staff has been steady with a 3.98 ERA and 1.27 WHIP.

At the plate, Aaron Judge has been the difference maker, hitting .325 with 47 home runs and 101 RBI. He leads a lineup that has hit 251 homers and carries a .454 slugging percentage. Giancarlo Stanton (20 home runs in limited at-bats) and Jazz Chisholm Jr. (29 homers). With power up and down the order, New York is a tough matchup for a young starter.

Minnesota Twins Preview

Minnesota has dropped three of its last four, scoring just 13 runs in those losses. Minnesota Trails first place in the American League Central by 18.5 games and is on the verge of being eliminated from postseason contention. Simeon Woods Richardson starts with a 6–4 record and 4.58 ERA. In 94.1 innings, he has allowed 16 home runs and 41 walks. Minnesota’s pitching staff holds a 4.60 ERA and a .260 opponent average.

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The offense is centered around Byron Buxton, who is batting .274 with 31 homers, 22 steals, and 76 RBI. Trevor Larnach (.252, 16 HRs) provides additional power for Minnesota, but overall, the team has a below-average slash line of .240/.313/.399 with 176 home runs. Catcher Ryan Jeffers remains sidelined.

Prediction New York Yankees vs Minnesota Twins

With Rodon’s strikeout ability against a lineup that has struck out often this season and New York’s advantage at the plate, the Yankees hold the clear edge. Minnesota will need Woods Richardson to limit his mistakes, which looks unlikely against Judge, Stanton, and company. Final Score Prediction: New York Yankees win 7-3.

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Best Picks:

  • New York Yankees -1.5
  • Carlos Rodon 6+ strikeouts
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