Pittsburgh Pirates vs Baltimore Orioles Picks and Prediction for Tuesday September 9 2025

By: Eddie Kline Published 09/09/2025, 01:00 AM ET

Pirates Preview

The Tuesday MLB schedule will get started with an interleague clash between the Pittsburgh Pirates and the Baltimore Orioles from Camden Yards. Be ready for the baseball season with all of our MLB predictions. The Pirates (64-80) have dropped 47 of their first 69 road games and are trapped in the NL Central Division cellar. On Sunday, Pittsburgh batters managed just five hits and struck out 12 times during a 10-2 home loss versus Milwaukee.

Rookie right-hander Mike Burrows (2-4 4.08 ERA) will make his 17th career major league start for the Pirates. Through 81 plus innings, Burrows has retired 82 batters by strikes and owns a respectable 1.26 WHIP.

Orioles Preview

The Baltimore Orioles have won six of their previous ten games and have been one of the most disappointing teams in the majors. On Sunday, Baltimore batters were retired by strikes 15 times during a 5-2 home loss versus the Los Angeles Dodgers. 3B Emmanuel Rivera went 2-for-4 with a run scored and an RBI in a losing effort for the Orioles (66-77).

The Orioles will counter with twenty-eight year old righty Kyle Bradish (0-1 3.60 ERA) in the series opener. Last time out, Bradish (4 IP) allowed two runs and fanned five batters during a 4-3 road victory against San Diego.

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Orioles vs Pirates Pick

Baltimore OF Tyler O’Neill (wrist) is currently on a rehab assignment with Double-A Chesapeake and should return to the lineup later this week. Through 144 games, Pittsburgh ranks 30th in OPS and 30th in runs scored. For the season, Baltimore ranks 17th in OPS and 17th in runs scored. Take the under. Final Score Prediction, Baltimore Orioles win 4-2.

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