Pittsburgh Pirates vs Milwaukee Brewers Picks and Predictions for Friday April 24 2026

By: Kim Smith Published 04/24/2026, 12:35 AM ET
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The Pittsburgh Pirates travel to take on the Milwaukee Brewers at American Family Field in Milwaukee, Wisconsin, on Friday, April 24, 2026, with first pitch scheduled for 7:40 PM and coverage available on ESPN Unlmtd and MLB.TV. The betting odds show Pittsburgh as a -136 favorite on the moneyline, while Milwaukee comes in at +113, with the total set at 7 runs. The Pirates are listed at -1.5 (+129) on the run line, while the Brewers are +1.5 (-156). This matchup brings together two teams with similar records looking to gain an edge, and readers are encouraged to check out free MLB picks for more daily baseball insights.

Starting Pitchers Set for a Competitive Matchup

Pittsburgh will send Paul Skenes to the mound, entering with a 3-1 record, a 3.27 ERA, and a 0.91 WHIP over 22.0 innings. He has allowed 13 hits while striking out 23 batters and issuing 7 walks, giving up two home runs. Milwaukee counters with Brandon Woodruff, who comes in with a 2-0 record, a 3.42 ERA, and a 0.93 WHIP across 23.2 innings. Woodruff has allowed 18 hits, struck out 20, walked 4, and surrendered three home runs.

Pittsburgh Bringing Balanced Play Into Milwaukee

The Pirates enter this game with a 14-11 overall record and a 6-6 mark on the road. Over their last five games, Pittsburgh has recently won over Texas and Tampa Bay, while also recently losing to Texas twice and Tampa Bay once. This stretch shows a team that has remained competitive, even while alternating wins and losses.

Pittsburgh is hitting .250 as a team with 122 runs scored on 209 hits, including 27 home runs. They have posted a .335 on-base percentage and a .391 slugging percentage. On the pitching side, the Pirates have recorded a 3.33 ERA with a 1.27 WHIP, allowing opponents to hit .224 while striking out 227 batters and issuing 98 walks.

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One of Pittsburghโ€™s key strengths is its ability to limit opposing hitters, as reflected by the .224 opponent batting average. This has helped support a strong ERA and has allowed the Pirates to stay competitive in a variety of game situations.

Milwaukee Looking to Respond at Home

The Brewers come into this matchup with a 13-11 overall record and a 7-5 mark at home. In their last five games, Milwaukee has recently won over Detroit and Miami, while also recently losing to Detroit twice and Miami once. This pattern highlights a team that has shown flashes of strong play but has not maintained consistency.

Milwaukee is hitting .239 with 120 runs scored on 183 hits, including 19 home runs. They hold a .342 on-base percentage and a .366 slugging percentage. On the pitching side, the Brewers carry a 3.93 ERA and a 1.34 WHIP, allowing opponents to hit .244 while striking out 204 batters and issuing 88 walks.

A notable weakness for Milwaukee is the higher WHIP of 1.34 compared to Pittsburghโ€™s 1.27, which suggests more baserunners allowed. This can create added pressure on their pitching staff, especially against a lineup capable of generating consistent offense.

Pittsburgh Pirates vs Milwaukee Brewers Picks and Prediction

Pittsburgh Pirates vs Milwaukee Brewers Pick

Pick: Pittsburgh Pirates Moneyline

Pittsburgh is the preferred side in this matchup due to its slightly stronger overall pitching metrics and ability to limit opposing hitters. The Pirates have a lower ERA and opponent batting average compared to Milwaukee, and their starting pitcher enters with a lower WHIP. While both teams have shown similar recent form, Pittsburghโ€™s pitching advantage gives them the edge.

Pittsburgh Pirates vs Milwaukee Brewers Total Pick

Pick: Under 7

I would lean toward the under in this matchup because both teams feature solid pitching numbers and starting pitchers with comparable ERAs and WHIPs. Pittsburgh has limited opponents to a .224 average, while Milwaukee has maintained a sub-4.00 ERA. With both sides capable of controlling the game on the mound, this matchup has the potential to stay under the total.

Final Score Prediction: Pittsburgh Pirates 4 โ€“ Milwaukee Brewers 2

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