Pittsburgh Pirates vs Milwaukee Brewers Picks and Predictions for Sunday April 26 2026

By: Kim Smith Published 04/26/2026, 01:05 AM ET
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The Pittsburgh Pirates travel to face the Milwaukee Brewers at American Family Field in Milwaukee, Wisconsin on Sunday, April 26, 2026, with first pitch scheduled for 2:10 PM and coverage available on ESPN Unlmtd and MLB.TV. The current betting odds list Milwaukee as a -131 favorite on the moneyline, while Pittsburgh comes in at +109. The total is set at 7.5 runs, with the over at -115 and the under at -105, while the run line shows Pittsburgh +1.5 at -207 and Milwaukee -1.5 at +169. Be sure to check out free MLB picks.

Starting Pitchers Preview

Pittsburgh is set to start Carmen Mlodzinski, while Milwaukee will counter with Kyle Harrison. Mlodzinski enters this matchup with a 1-1 record, a 3.28 ERA, and a 1.42 WHIP across 24.2 innings. He has allowed 25 hits while striking out 26 and walking 10, and notably has not allowed a home run. On the other side, Harrison comes in at 1-1 with a 3.06 ERA and a 1.30 WHIP over 17.2 innings. He has allowed 16 hits while striking out 18 and walking seven, along with giving up two home runs.

Pittsburgh Carrying Momentum into Milwaukee

Pittsburgh enters this contest with a 15-11 overall record and a 7-6 mark on the road. The Pirates recently won over Milwaukee in a 6-0 result and have alternated wins and losses in their last five games, including victories against Texas and Tampa Bay along with losses in that same stretch. This recent form shows a team capable of producing strong performances but still working toward consistent results.

Offensively, Pittsburgh is hitting .246 with 129 runs scored and 223 hits. They have produced 29 home runs while posting a .330 on-base percentage and a .386 slugging percentage. On the pitching side, the Pirates have been solid, carrying a 3.32 ERA with a 1.25 WHIP, allowing a .220 opponent batting average while recording 243 strikeouts and issuing 104 walks.

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A key strength for Pittsburgh is their ability to limit opposing hitters. The .220 opponent batting average stands out as one of the better marks in this matchup, indicating that their pitching staff has been effective at controlling contact and keeping opposing offenses in check.

Milwaukee Searching for Consistency at Home

Milwaukee comes into this matchup with a 13-12 overall record and a 7-6 mark at home. The Brewers recently lost to Pittsburgh in a 6-0 game and have dropped three of their last four contests, including losses to Detroit and Miami. While they did pick up a win during that stretch, their recent results show a team trying to regain consistency.

The Brewers are hitting .233 with 124 runs scored and 193 hits. They have added 19 home runs while carrying a .333 on-base percentage and a .354 slugging percentage. On the mound, Milwaukee has a 3.98 ERA with a 1.33 WHIP, allowing a .243 opponent batting average while recording 217 strikeouts and issuing 94 walks.

One area of concern for Milwaukee is offensive production. Compared to Pittsburgh, the Brewers have a lower batting average, fewer hits, and fewer home runs, which can make it difficult to generate consistent scoring opportunities, especially against a pitching staff that has been effective at limiting contact.

Pittsburgh Pirates vs Milwaukee Brewers Picks and Prediction

Pittsburgh Pirates vs Milwaukee Brewers Pick

Pick: Pittsburgh Pirates Moneyline

Pittsburgh is the pick on the moneyline based on their overall balance and pitching performance. The Pirates have been more effective at limiting opposing hitters, as shown by their .220 opponent batting average and lower ERA compared to Milwaukee. They also hold advantages in batting average, hits, and home runs, giving them a more complete offensive profile. With recent success against Milwaukee and stronger pitching metrics, Pittsburgh has the edge in this matchup.

Pittsburgh Pirates vs Milwaukee Brewers Total Pick

Pick: Under 7.5

I’m leaning toward the under 7.5 in this matchup because both teams have shown the ability to limit scoring through their pitching. Pittsburgh’s pitching staff has been particularly effective at controlling contact, while Milwaukee has also kept its ERA under 4.00. Offensively, neither team has overwhelming power numbers, especially Milwaukee, which suggests this game could stay at a moderate pace. With both starting pitchers posting solid ERA figures, the under looks like the stronger play.

Final Score Prediction: Pittsburgh Pirates 4 – Milwaukee Brewers 3

This prediction was written before the completion of game play on Saturday.

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