San Diego Padres vs New York Mets Picks and Prediction for Thursday September 18 2025

By: Eddie Kline Published 09/18/2025, 12:35 AM ET
Use Code PPWC

Padres Preview

In Thursday afternoon MLB action, the San Diego Padres and the New York Mets will wrap up their series from Citi Field. Be ready for the baseball season with all of our MLB predictions. The Padres (83-69) have won seven of their last 11 games and are sitting comfortably in second place in the NL Wild Card standings. Last night, Manny Machado’s fifth inning grand slam propelled San Diego to a 7-4 road triumph.

Twenty-six year old righty Randy Vasquez (5-6 3.72 ERA) will make his 25th start of the year for the Padres. Last time out, Vasquez fired six shutout frames and fanned nine batters during a 2-0 home victory versus lowly Colorado.

Mets Preview

The New York Mets have dropped nine of their previous 11 games and are clinging to a 1.5 game lead over Arizona for the final NL Wild Card spot. On Wednesday, New York SP David Peterson (9-6) was roughed up for six runs in five innings. Starling Marte, Juan Soto, Pete Alonso, and Francisco Alvarez all went deep in a losing effort for the Mets (78-74).

Rookie right-hander Jonah Tong (1-2 8.49 ERA) will make his fourth career major league start for the Mets. Last time out, Tong was rocked for six runs and recorded just two outs during an 8-3 home loss versus Texas.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Padres vs Mets Pick

San Diego SS Xander Bogaerts (foot) has resumed baseball activities and hopes to return later this month. Through 152 games, San Diego ranks 17th in OPS and 23rd in runs scored. For the season, New York ranks 7th in OPS and 11th in runs scored. Take the Mets to win at home. Final Score Prediction, New York Mets win 5-3.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $200 in Bonuses Instantly!

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Odds Requirements -500
Cashable No
Video: World Cup: Mexico vs England BEST Bets & Predictions | July 5, 2026
World Cup: Mexico vs England BEST Bets & Predictions | July 5, 2026
Video: Brazil vs Norway: The Bet You AREN'T Thinking Of! | BEST World Cup Predictions | July 5, 2026
Brazil vs Norway: The Bet You AREN'T Thinking Of! | BEST World Cup Predictions | July 5, 2026
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright Β© 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.