San Francisco Giants vs Chicago Cubs Picks and Prediction for Sunday June 7 2026
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The San Francisco Giants and Chicago Cubs meet at Wrigley Field in Chicago, Illinois, on Sunday, June 7, 2026, at 8:30 PM ET. The game will be televised on NBC and Peacock. At the time of this writing the odds were not released. Be sure to check out our free MLB picks.
Starting Pitchers
The Giants are expected to start Trevor McDonald, who enters the game with a 2-3 record, a 4.50 ERA, and a 1.15 WHIP across 34.0 innings. He has allowed 30 hits, struck out 31 batters, walked 9, and surrendered 3 home runs. The Cubs are expected to counter with Jameson Taillon, who is 2-5 with a 5.13 ERA and a 1.26 WHIP over 66.2 innings. He has allowed 63 hits, recorded 57 strikeouts, issued 21 walks, and given up 20 home runs.
San Francisco Riding a Surge Into the Finale
The Giants enter this matchup with a 26-38 overall record and a 14-22 road record. San Francisco recently defeated Chicago 18-3, beat Milwaukee 12-9, defeated Milwaukee 1-0, lost to Milwaukee 8-3, and lost to Milwaukee 16-2. The Giants have won three of their last five games and are coming off their most impressive offensive performance of the season based on the scores provided.
San Francisco is batting .260 with 268 runs, 577 hits, and 65 home runs. The Giants own a .307 on-base percentage and a .419 slugging percentage. Their pitching staff has posted a 4.56 ERA and a 1.41 WHIP while allowing opponents to hit .253. They have drawn 259 walks and recorded 500 strikeouts.
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The Giants' greatest strength is their ability to put the ball in play. They lead this matchup in batting average and hits, and they showed their offensive potential with an 18-run outburst in the most recent game. The weakness has been run prevention, as their ERA and WHIP are both higher than Chicago's.
Chicago Searching for a Bounce-Back Effort
The Cubs enter this contest with a 33-31 overall record and a 19-14 home record. Chicago recently lost to San Francisco 18-3, defeated the Athletics 7-6, lost to the Athletics 5-4 in 10 innings, lost to the Athletics 2-1, and lost to St. Louis 5-1. The Cubs have won just one of their last five games and will be looking to respond after Friday's lopsided defeat.
Chicago is batting .240 with 299 runs, 521 hits, and 72 home runs. The Cubs own a .333 on-base percentage and a .390 slugging percentage. On the mound, they have a 4.39 ERA and a 1.25 WHIP while allowing opponents to hit .242. Chicago has also recorded 507 strikeouts and issued 190 walks.
The Cubs' biggest advantage is run production and overall pitching efficiency. They have scored more runs, hit more home runs, own a better ERA, a lower WHIP, and a lower opponent batting average than San Francisco. Those season-long numbers remain strong despite the recent loss.
San Francisco Giants vs Chicago Cubs Picks and Prediction
San Francisco Giants vs Chicago Cubs Pick
- Pick: Chicago Cubs Moneyline
Chicago gets the nod despite the 18-3 loss in the most recent meeting. The Cubs have the better overall record, the better home record, and stronger season-long numbers in several important categories, including runs scored, home runs, ERA, WHIP, and opponent batting average. While San Francisco has played better over the last few games, the larger body of work still favors Chicago.
San Francisco Giants vs Chicago Cubs Total Pick
- Pick: Take the over if the total is set at 8.5.
I like the over because both teams have recently been involved in high-scoring games. San Francisco's last five contests produced totals of 21, 21, 1, 11, and 18 runs. Chicago's most recent game ended with 21 total runs as well. Both starting pitchers enter with ERAs above 4.50, which also supports a higher-scoring outlook.
Final Score Prediction: Chicago Cubs 6 – San Francisco Giants 5
This prediction was written before the completion of game play on Saturday.
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