San Francisco Giants vs Miami Marlins Picks and Prediction for Sunday June 21 2026

By: Eddie Kline Published 06/21/2026, 01:05 AM ET

Giants Preview

LoanDepot Park will play host to a Sunday afternoon MLB clash between the San Francisco Giants and the Miami Marlins. Be ready for the baseball season with all of our MLB predictions. The Giants (31-45) have dropped 25 of their first 42 road games and are an underwhelming 18 games out of first place in the NL West Division. Last night, San Francisco OF Casey Schmitt homered and double twice during a 6-3 road loss against Miami.

Twenty-nine year old righty Logan Webb (4-4 3.46 ERA) will take the mound for the Giants in this matchup. In his last start, Webb (8 IP) allowed one run and retired seven batters by strikes during a 5-1 home victory versus Chicago.

Marlins Preview

The Miami Marlins have won three straight games and have outscored their opponents 22-10 during that stretch. During Saturday’s home victory, OF Heriberto Hernandez capped Miami’s four-run fourth inning eruption with a two-run blast to left field. SP Max Meyer (8-0) fanned seven batters in five innings to earn the win for the Marlins (39-38), who moved to 25-16 at home.

Miami skipper Clayton McCullough will give the nod to twenty-seven year old righty Ryan Gusto (0-2 7.24 ERA) in the series finale. Last time out, Gusto (4.2 IP) was roughed up for eight hits and five runs during a 7-0 road loss against Philadelphia.

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Giants vs Marlins Pick

San Francisco OF Heliot Ramos (quadriceps) is on a rehab assignment with Triple-A Sacramento and should rejoin the lineup this week. Through 76 games, San Francisco ranks 12th in OPS and 21st in runs scored. For the season, Miami ranks 19th in OPS and 16th in runs scored. Take the under. Final Score Prediction, San Francisco Giants win 4-2.

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