Seattle Mariners vs Houston Astros Picks and Predictions for Saturday September 20 2025
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Mariners Preview
The Seattle Mariners are heading to Daikin Park on Saturday, where they will take on the Houston Astros. Get the rest of our free MLB picks here! The Mariners currently sit tied for first in the AL West, entering this game with an 84-69 record. Seattle brings momentum into Houston after shutting out the Royals 2-0 on Thursday, thanks to a strong outing from Luis Castillo and a timely RBI from Jorge Polanco. George Kirby will be the starting pitcher for Seattle in this game, he enters with a 9-7 record and a 4.46 ERA, and has struck out 120 batters in 115 innings. Seattle is sitting with a .244 batting average, with 4.8 runs per game and 223 home runs this season. Their bullpen has posted a team ERA of 3.91 and a WHIP near 1.24.
Astros Preview
The Houston Astros also enter at 84-69, locked in a fierce AL West fight with Seattle. Houston is coming off a series sweep of the Texas Rangers, with standout performances by Christian Walker and Jose Altuve. Framber Valdez gets the ball for Houston, sporting a 12-10 record and a 3.59 ERA, with 173 strikeouts over 180 innings. The Astros are batting .252 overall, with 169 home runs and a team ERA of 3.83, supported by a deep bullpen and solid starting rotation depth.
Mariners vs Astros Pick
This is an important series as the Mariners and Astros both fight for the top spot in the AL West. Expect Valdez to give the Astros the edge in this game, as he has been consistently good all year long. Final score prediction, Astros win 4-3. The play here is taking Houston -110.
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