Seattle Mariners vs St. Louis Cardinals Picks and Predictions for Sunday April 26 2026
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The Seattle Mariners travel to face the St. Louis Cardinals at Busch Stadium in St. Louis, Missouri on Sunday, April 26, 2026, with first pitch scheduled for 2:15 PM and coverage available on MLB.TV. The current betting odds list Seattle as a -149 favorite on the moneyline, while St. Louis comes in at +123. The total is set at 8 runs, with the over at -112 and the under at -108, while the run line shows Seattle -1.5 at +119 and St. Louis +1.5 at -143. Make sure to check out free MLB picks.
Starting Pitchers Preview
Seattle is set to start Emerson Hancock, while St. Louis will counter with Michael McGreevy. Hancock enters this matchup with a 2-1 record, a 2.83 ERA, and an impressive 0.87 WHIP across 28.2 innings. He has allowed 21 hits while striking out 28 and walking just four, though he has given up five home runs. On the other side, McGreevy comes in at 1-2 with a 3.29 ERA and a 0.91 WHIP over 27.1 innings. He has allowed 20 hits while striking out 15 and walking five, while surrendering four home runs.
Seattle Finding Its Groove Despite Road Record
Seattle enters this contest with a 13-15 overall record and a 3-8 mark on the road. The Mariners have been playing better recently, winning three of their last five games, including back-to-back victories over St. Louis and a win against Oakland. They also dropped two games in that stretch, but their recent results show signs of improvement and growing consistency.
Offensively, Seattle is hitting .223 with 104 runs scored and 197 hits. They have produced 26 home runs while posting a .319 on-base percentage and a .360 slugging percentage. On the pitching side, the Mariners have been strong, carrying a 3.37 ERA with a 1.21 WHIP, allowing a .254 opponent batting average while recording 222 strikeouts and issuing just 64 walks.
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A key strength for Seattle is their pitching control. With a low WHIP and a relatively small number of walks issued, they have done a solid job of limiting free baserunners, which can help keep games within reach even when the offense is not at its best.
St. Louis Searching for Stability at Home
St. Louis comes into this matchup with a 14-12 overall record and a 7-7 mark at home. The Cardinals have struggled in recent games, losing to Seattle in consecutive matchups and dropping multiple games in their last five outings, with just one win during that stretch. Their recent form reflects a team trying to regain momentum.
The Cardinals are hitting .230 with 114 runs scored and 191 hits. They have added 27 home runs while carrying a .319 on-base percentage and a .371 slugging percentage. On the mound, St. Louis has a 4.70 ERA with a 1.41 WHIP, allowing a .252 opponent batting average while recording 164 strikeouts and issuing 102 walks.
One concern for St. Louis is their pitching performance. The higher ERA and WHIP compared to Seattle indicate that limiting opposing offenses has been a challenge, which can be especially problematic against a team that has shown recent improvement.
Seattle Mariners vs St. Louis Cardinals Picks and Prediction
Seattle Mariners vs St. Louis Cardinals Pick
Pick: Seattle Mariners Moneyline
Seattle is the preferred side in this matchup due to their advantage on the mound and recent success in this series. The Mariners have won back-to-back games against St. Louis and hold the edge in ERA and WHIP, showing a stronger ability to limit opposing hitters. Hancock’s numbers also provide a slight advantage over McGreevy, particularly in strikeouts and overall control. With Seattle’s pitching strength and recent momentum, they have the upper hand.
Seattle Mariners vs St. Louis Cardinals Total Pick
Pick: Under 8
I’m leaning toward the under 8 in this matchup because Seattle’s pitching staff has been effective at limiting runs, as reflected in their 3.37 ERA and low walk totals. While St. Louis has shown some offensive capability, their recent struggles and Seattle’s ability to control baserunners suggest this game could remain at a moderate scoring pace. With both starting pitchers posting solid WHIP numbers, I expect a relatively controlled game.
Final Score Prediction: Seattle Mariners 4 – St. Louis Cardinals 3
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