St. Louis Cardinals vs Colorado Rockies Picks and Prediction for Sunday, September 6, 2026

By: David Anicetti Published 09/06/2026, 12:10 AM ET

The St. Louis Cardinals and Colorado Rockies meet Sunday at Coors Field, with the opening pitch scheduled for 3:10 PM ET and the game televised on MLB.TV. St. Louis is 71-71, third in the NL Central and 17 games behind Milwaukee. Colorado is 54-87, fifth in the NL West and 30 games behind the Los Angeles Dodgers. The Cardinals are four games behind the final NL Wild Card spot. St. Louis is 4-6 over its last 10 games, while Colorado is also 4-6. Cash in a winning ticket with our free MLB picks.

St. Louis Cardinals Preview

St. Louis is batting .242 with a .316 OBP and .385 slugging percentage while scoring 640 runs. Jordan Walker leads the Cardinals with a .289 average, 28 home runs and 156 hits, while Alec Burleson has produced a team-high 102 RBI with 21 homers. Walker also has 100 RBI and a .504 slugging percentage.

The Cardinals carry a 4.24 team ERA and 1.35 WHIP, with opponents batting .253. St. Louis has won three of its last four games, scoring 30 runs during that stretch. The Cardinals opened this series with a 7-6 victory and enter Sunday with a 37-33 road record.

Injuries: Masyn Winn (SS), Everson Pereira (RF), JJ Wetherholt (2B) and Blaze Jordan (3B) are on the 10-day IL. Peter Strzelecki (RP) is on the 15-day IL.

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Colorado Rockies Preview

Colorado has better season-long hitting numbers, batting .253 with a .324 OBP and .417 slugging percentage while scoring 661 runs. TJ Rumfield leads Colorado with a .295 average, .388 OBP and 142 hits. Hunter Goodman supplies the biggest power threat with 36 home runs and a team-high 74 RBI.

Pitching remains Colorado's biggest statistical disadvantage. The Rockies have a 5.42 ERA and 1.52 WHIP while opponents are batting .287. Colorado has allowed 1,404 hits across 1,231.2 innings. The Rockies have lost three of their last five games and are 29-40 at Coors Field this season.

Injuries: McCade Brown (SP) and Kris Bryant (DH) are on the 60-day IL. Willi Castro (2B) is day-to-day, Kyle Karros (3B) is on the 7-day IL, and Kyle Freeland (SP) is on the 15-day IL.

Pitching Matchup

St. Louis Cardinals - Kyle Leahy

Kyle Leahy is 10-4 with a 3.13 ERA and 1.31 WHIP through 129.1 innings. The right-hander has allowed 131 hits and 13 home runs while recording 118 strikeouts and issuing 38 walks.

Colorado Rockies - Tanner Gordon

Tanner Gordon is 1-4 with a 5.18 ERA and 1.40 WHIP across 88.2 innings. The right-hander has allowed 108 hits and 17 home runs while striking out 72 and issuing 16 walks.

St. Louis Cardinals vs Colorado Rockies Prediction

St. Louis has the stronger pitching setup for this matchup, starting with Leahy's 3.13 ERA compared with Gordon's 5.18 mark. Colorado owns the better season batting average and slugging percentage, but the Rockies' pitching staff has allowed opponents to hit .287 while posting a 5.42 ERA. St. Louis has also won three of its last four games and took the series opener 7-6. With the Cardinals holding the stronger starting and overall pitching numbers, St. Louis will win another high-scoring game at Coors Field. Final Score Prediction: St. Louis Cardinals win, 7-5.

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