St. Louis Cardinals vs Milwaukee Brewers Picks and Prediction for Tuesday May 26 2026
Use Code PPWC
The St. Louis Cardinals travel to American Family Field in Milwaukee, Wisconsin, for a Tuesday night matchup against the Milwaukee Brewers on May 26, 2026. First pitch is scheduled for 7:40 PM ET with coverage available on MLB.TV. Both teams enter this matchup near the top of their divisions, setting up an important contest between two clubs that have played strong baseball for much of the season. Milwaukee enters with the edge in the matchup predictor at 64.2 percent while St. Louis sits at 35.8 percent. Be sure to check out our free MLB picks.
Starting Pitchers Set for Tuesday Night in Milwaukee
Michael McGreevy gets the start for St. Louis carrying a 3-3 record with an impressive 2.40 ERA and 0.99 WHIP over 56.1 innings pitched this season. He has allowed 44 hits while striking out 37 batters and surrendering seven home runs. Milwaukee counters with Kyle Harrison, who enters the matchup with a dominant 5-1 record alongside a 1.77 ERA and 1.07 WHIP across 45.2 innings pitched. Harrison has allowed 35 hits while recording 59 strikeouts and giving up only three home runs this season.
Cardinals Looking to Improve Recent Consistency
St. Louis enters Tuesday’s matchup with a 29-22 overall record and an excellent 16-9 road record this season. The Cardinals recently lost to Cincinnati 7-6 in 11 innings after previously recently won over the Reds 8-1. Before that, St. Louis recently lost to Pittsburgh by scores of 6-2 and 7-0 after recently won over the Pirates 9-6 in 10 innings. The Cardinals have won two of their last five games entering this important divisional matchup.
The Cardinals are batting .242 as a team while scoring 233 runs and collecting 416 hits this season. St. Louis has also produced 60 home runs while posting a .323 on-base percentage and a .393 slugging percentage. On the mound, the Cardinals carry a 4.20 ERA and 1.37 WHIP while allowing opponents to hit .254 against them. St. Louis pitchers have also recorded 380 strikeouts and issued 190 walks this season.
Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Subscribe Now
One of the biggest strengths for St. Louis entering this game has been road performance. The Cardinals have won 16 road games already this season and continue showing strong offensive power with 60 home runs. However, the pitching staff has struggled more consistently compared to Milwaukee, especially in opponent batting average and ERA.
Brewers Trying to Defend Home Field
Milwaukee enters the contest with a 30-20 overall record and a 16-11 home mark this season. The Brewers recently lost to Los Angeles by scores of 5-1 and 11-3 after previously recently won over the Dodgers 5-1. Before that, Milwaukee recently won over Chicago by scores of 5-0 and 5-2. The Brewers have won three of their last five games overall entering Tuesday night.
The Brewers are batting .246 as a team with 246 runs scored and 413 hits this season. Milwaukee has hit 34 home runs while posting a .333 on-base percentage and a .361 slugging percentage. The pitching staff has been the biggest strength with a 3.31 ERA and 1.21 WHIP while limiting opponents to a .220 batting average. Milwaukee pitchers have also generated 488 strikeouts this season.
Milwaukee’s biggest advantage entering this matchup has clearly been pitching efficiency. The Brewers own the lower ERA, lower WHIP, and much stronger opponent batting average compared to St. Louis. Kyle Harrison has also been dominant throughout the season, giving Milwaukee another edge in this matchup.
St. Louis Cardinals vs Milwaukee Brewers Picks and Prediction
St. Louis Cardinals vs Milwaukee Brewers Pick
- Pick: Milwaukee Brewers Moneyline
Milwaukee enters this matchup with the stronger pitching profile and home-field advantage. The Brewers have consistently limited opposing offenses with a 3.31 ERA and opponents batting only .220 against them this season. Kyle Harrison’s excellent 1.77 ERA and 59 strikeouts in 45.2 innings also create a difficult matchup for St. Louis. While the Cardinals have been solid on the road, Milwaukee’s pitching advantage gives the Brewers the edge here.
St. Louis Cardinals vs Milwaukee Brewers Total Pick
- Pick: Under 8
I like the under in this matchup because both starting pitchers enter with strong numbers and Milwaukee games have frequently stayed lower scoring recently. The Brewers recently won games by scores of 5-1, 5-0, and 5-2, while St. Louis has also played several controlled games during the last week. With both starters carrying ERAs under 2.50, this matchup could remain tight throughout the night.
Final Score Prediction: Milwaukee Brewers 4 – St. Louis Cardinals 2
This prediction was written before the completion of game play on Monday.
Never Tried Picks and Parlays? Now Is Your Chance
- Get your first daily picks package for ONLY $1 using coupon code BUCK
- If the pick loses, we credit your account with 3 Flex Picks
- If the pick wins, we still give you 1 Flex Pick on the house
- Win or lose, you walk away ahead. One dollar. No catch.
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days
New DraftKings Customers: Spend $5+ Get $200 in Bonuses Instantly!
