Tampa Bay Rays vs Baltimore Orioles Picks and Prediction for Wednesday May 27 2026

By: Kim Smith Published 05/27/2026, 12:40 AM ET

The Tampa Bay Rays travel to face the Baltimore Orioles on Wednesday, May 27, 2026, at Oriole Park at Camden Yards in Baltimore, Maryland. First pitch is scheduled for 6:35 PM ET with television coverage available on MLB.TV and FS1. The weather forecast for the game is 75 degrees. At the time of this writing the odds were not released. Be sure to check out our free MLB picks.

Starting Pitchers Highlight Wednesday Night Matchup

The Rays are expected to start Steven Matz, who enters the game with a 4-1 record, a 3.70 ERA, a 1.11 WHIP, 41.1 innings pitched, 31 hits allowed, 33 strikeouts, 15 walks, and six home runs allowed. Baltimore is scheduled to counter with Chris Bassitt, who comes in at 4-3 with a 5.51 ERA, a 1.67 WHIP, 47.1 innings pitched, 60 hits allowed, 34 strikeouts, 19 walks, and four home runs allowed. Tampa Bay holds the statistical edge in the starting pitching matchup based on ERA, WHIP, and hits allowed.

Tampa Bay Continues Strong Overall Season

Tampa Bay enters this matchup with a 34-17 overall record and a 15-12 road record. The Rays recently lost to Baltimore by a 9-7 score in 13 innings after previously losing to the Yankees 2-0. Before those losses, Tampa Bay had recently won over Baltimore and New York during a strong stretch that included consecutive victories against the Orioles by scores of 5-3 and 4-1. Despite dropping two straight games, the Rays continue to own one of the stronger records among the teams provided.

The Rays are batting .260 as a team with 243 runs, 449 hits, 43 home runs, a .334 on-base percentage, and a .389 slugging percentage. Tampa Bay’s pitching staff has been impressive with a 3.50 ERA, a 1.20 WHIP, 160 walks, 396 strikeouts, and a .228 opponent batting average. The Rays also hold a strong 20-8 record in night games this season.

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One of Tampa Bay’s biggest strengths entering this matchup is overall consistency on both sides of the ball. The Rays hold advantages over Baltimore in batting average, on-base percentage, ERA, WHIP, and opponent batting average. Even though the home run totals are lower than Baltimore’s, Tampa Bay has still found ways to consistently generate offense while preventing runs at a much stronger rate.

Baltimore Searching for Momentum at Home

Baltimore comes into Wednesday’s game with a 24-30 overall record and a 15-13 home record. The Orioles recently won over Tampa Bay 9-7 in 13 innings after splitting games against Detroit over the weekend. Baltimore also recently won over Detroit by scores of 5-3 and 7-4 before previously losing to Tampa Bay earlier in the week. The Orioles have now won three of their last five games and have shown flashes of offensive production during that stretch.

The Orioles are batting .233 with 237 runs, 420 hits, 59 home runs, a .315 on-base percentage, and a .386 slugging percentage. Baltimore’s pitching staff owns a 4.80 ERA, a 1.43 WHIP, 202 walks, 437 strikeouts, and a .260 opponent batting average. The Orioles have produced more home runs than Tampa Bay this season, but the overall pitching numbers have created problems throughout the year.

The key challenge for Baltimore entering this game is run prevention. The Orioles have allowed opponents to hit .260 against them while carrying a 4.80 ERA and a 1.43 WHIP. While the offense has delivered enough power to stay competitive in many games, the inconsistency on the mound has made it difficult to sustain winning stretches against stronger opponents.

Tampa Bay Rays vs Baltimore Orioles Picks and Prediction

Tampa Bay Rays vs Baltimore Orioles Pick

  • Pick: Tampa Bay Rays Moneyline

Tampa Bay is the stronger side entering this matchup based on both team and pitching statistics. The Rays hold clear advantages in ERA, WHIP, opponent batting average, batting average, and on-base percentage. Tampa Bay also owns the better overall record and has already recently won over Baltimore twice during this series stretch. With the starting pitching numbers favoring the Rays as well, Tampa Bay looks positioned to bounce back after the extra-innings loss.

Tampa Bay Rays vs Baltimore Orioles Total Pick

  • Pick: Take the over if the total is set at 9.

I would lean toward the over if the total is set at 9 because Baltimore’s pitching staff has consistently allowed offense throughout the season, while the most recent meeting between these teams produced 16 total runs. Tampa Bay has been productive offensively all season with a .260 batting average and 243 runs scored, and Baltimore has also shown power with 59 home runs. The recent 9-7 game between these teams suggests another matchup where scoring opportunities could continue to develop.

Final Score Prediction: Tampa Bay Rays 6 – Baltimore Orioles 4

This prediction was written before the completion of game play on Tuesday.

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