Tampa Bay Rays vs Baltimore Orioles Picks and Prediction for Wednesday September 24 2025

By: Eddie Kline Published 09/24/2025, 12:55 AM ET

Rays Preview

Beautiful Camden Yards will play host to a Wednesday night MLB clash between the Tampa Bay Rays and the Baltimore Orioles. Be ready for the baseball season with all of our MLB predictions. The Rays (76-81) have dropped seven of their previous 11 games and have been eliminated from postseason contention. Last night, Tampa Bay batters went 0-for-7 with runners in scoring position during a 6-0 road loss against Baltimore.

Twenty-six year old righty Shane Baz (10-12 4.99 ERA) will make his final start of the year for the Rays. Last time out, Baz fired five shutout frames and fanned four batters during a 4-0 home victory versus Toronto.

Orioles Preview

The Baltimore Orioles have won 12 of their 20 games in the month of September and are trying to climb out of the AL East Division cellar. During Tuesday’s home victory, Baltimore OF Colton Cowser went 2-for-4 with a home run and scored twice. SP Dean Kremer (11-10) allowed just one hit across six plus shutout frames to earn the win for the Orioles (74-83), who improved to 38-41 at home.

Thirty-one year old righty Tyler Wells (2-0 2.04 ERA) will make his fourth start of the season for the Orioles. Through 17 plus innings, Wells has allowed just one long ball and has retired 14 batters by strikes.

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Rays vs Orioles Pick

Tampa Bay SS Taylor Walls underwent successful sports hernia surgery and will miss the remainder of the season. Through 157 games, Tampa Bay ranks 14th in OPS and 15th in runs scored. For the season, Baltimore ranks 21st in OPS and 24th in runs scored. Take the Orioles to win at home. Final Score Prediction, Baltimore Orioles win 5-3.

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