Tampa Bay Rays vs New York Yankees Picks, Prediction, Odds, and Line Movement for Wednesday September 23 2026

By: Kyle Kargel Published 09/23/2026, 08:10 AM ET
Rays vs Yankees prediction

The Tampa Bay Rays and New York Yankees continue their four-game series Wednesday night at Yankee Stadium, and this Rays vs Yankees prediction features one of the most aggressive line moves on the board. Tampa Bay leads the AL East at 96-61, six games clear of the 90-67 Yankees, yet the market has pushed New York from -142 all the way to -157 behind Gerrit Cole. The clubs split Monday's doubleheader, with the Yankees winning the opener 2-0 and the Rays answering 6-1 in the nightcap, and both results reinforced how much pitching has controlled this series. With two elite staffs, a total of just 7 and sharp movement on both the side and the total, there is plenty to dig into. For more betting edges throughout the league, check out our full slate of MLB picks, then read on for the side, the total and the projected final score.

TLDR: Quick Picks and Prediction

  • Side Pick: New York Yankees Moneyline (-157)
  • Total Pick: Under 7 (-120)
  • Projected Final Score: Yankees 4, Rays 2

Odds and Line Movement

Current Odds

Team Moneyline Run Line Total
Tampa Bay Rays +130 +1.5 (-180) Over 7 (+100)
New York Yankees -157 -1.5 (+148) Under 7 (-120)

Line Movement - Moneyline

Date Tampa Bay NY Yankees Public ($, #)
09/23 +130 -157 NYY 87%, NYY 91%
09/23 +131 -158 NYY 75%, NYY 92%
09/23 +130 -158 NYY 75%, NYY 92%
09/23 +131 -158 NYY 75%, NYY 92%
09/23 +130 -158 NYY 75%, NYY 92%
09/23 +131 -158 NYY 75%, NYY 92%
09/23 +130 -158 NYY 75%, NYY 93%
09/23 +130 -157 NYY 75%, NYY 93%
09/23 +129 -156 NYY 90%, NYY 95%
09/23 +129 -157 NYY 89%, NYY 95%
09/22 +128 -155 NYY 92%, NYY 87%
09/22 +123 -149 NYY 82%, NYY 75%
09/22 +118 -142 NYY 83%, NYY 83%
09/22 +114 -142 NYY 83%, NYY 83%
09/22 +114 -137 NYY 83%, NYY 83%
09/22 +118 -142 -

This side has seen significant movement toward New York. The Yankees opened at -142 with Tampa Bay at +118, dipped briefly to -137, and then climbed steadily to -149, -155 and as high as -158. The Rays drifted from +118 all the way to +131 before settling at +130. Public support has been heavy the entire way, with New York drawing between 75% and 92% of the money and as much as 95% of the tickets at different points. The latest split shows 87% of the money and 91% of the tickets on the Yankees.

A move of roughly 15 cents on a baseball moneyline is substantial, and the market has made clear it views Cole and the home side as the right play despite the Rays holding the better record. Bettors who backed New York early got the best of the number, but the price has now stabilized in the -156 to -158 range, which suggests the market has found its level.

Line Movement - Total

Date Over Under Public ($, #)
09/23 7 +100 7 -120 OV 94%, OV 60%
09/23 7 -105 7 -114 OV 99%, OV 75%
09/22 7 -107 7 -113 OV 100%, OV 100%
09/22 7 -108 7 -112 OV 100%, OV 100%
09/22 7 -107 7 -112 OV 100%, OV 100%
09/22 7 -108 7 -112 -
09/22 7 -115 7 -105 -
09/22 7 -112 7 -108 -
09/22 7 -115 7 -105 -
09/22 7 -112 7 -108 -
09/22 7 -115 7 -105 -
09/22 7 -112 7 -108 -
09/22 7 -115 7 -105 -
09/22 7 -112 7 -108 -
09/22 7 -115 7 -105 -

The total tells the sharpest story in this matchup. It opened at 7 with the Over favored at -115 and the Under at -105, and the price bounced between those two levels several times early. Then the market flipped. The Under became the favored side at -112, then -113, -114 and now -120, while the Over has fallen all the way to even money at +100.

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That swing happened while the public was hammering the Over. The high side has drawn as much as 100% of the money and tickets, and it still holds 94% of the money and 60% of the tickets in the latest update. When the Under goes from -105 to -120 against that kind of one-sided public action, it is a clear case of reverse line movement. The number has stayed at 7, but the price shift is a strong signal that respected money is on the Under.

Key Matchups and Game Preview: Rays vs Yankees

Monday's doubleheader showed both sides of this rivalry. New York's pitching carried a 2-0 shutout in the opener, and Tampa Bay flipped the script with a 6-1 win in the nightcap. Wednesday sets up as another game where pitching takes center stage, with a strikeout-heavy lefty facing one of the most accomplished right-handers in the league.

Seymour vs Cole: Yankees Hold the Steadier Arm

New York hands the ball to Gerrit Cole, who is 9-9 with a 3.63 ERA and 1.10 WHIP over 121.1 innings. Cole has allowed 112 hits while striking out 123 against just 22 walks. That walk total is the standout number. Cole is not giving hitters free passes, which forces opponents to string together hits to score. Against a Tampa Bay lineup built more on contact than power, that kind of command makes it very difficult to generate big innings. Cole brings the more reliable run-prevention profile in this matchup, and the market has priced him accordingly.

Rays Lefty Seymour Misses Bats but Allows Power

Tampa Bay counters with left-hander Ian Seymour, who is 9-7 with a 4.38 ERA and an impressive 1.17 WHIP across 127.1 innings. Seymour has allowed 113 hits while piling up 155 strikeouts against only 36 walks. That strikeout total is outstanding, and his command is sharp as well. The concern is the long ball. Seymour has surrendered 25 home runs, and that has been the main reason his ERA sits well above what his WHIP would suggest. Facing a Yankees lineup with 217 homers, that vulnerability is the biggest threat to his outing.

Yankees Power Bats Rice and Bellinger

New York has not been a high-average team, batting .234 with a .310 OBP, but it has produced significantly more power than Tampa Bay with 217 home runs. Ben Rice leads the charge with 39 homers and 95 RBI, giving the Yankees a direct counter to Seymour's home run issues. Cody Bellinger adds balance with a .268 average, .343 OBP and .436 slugging percentage. In a low-scoring game, one or two swings from this group could be the difference, and that is the core of the case for New York.

Tampa Bay Contact Attack Led by Caminero and Simpson

The Rays have been the better contact-hitting club, batting .258 with a .327 OBP, though their 164 home runs trail New York by a wide margin. Junior Caminero has been the centerpiece with 41 homers and 97 RBI while batting .275, making him the most dangerous bat in this game. Chandler Simpson leads the club with a .309 average and gives Tampa Bay a speed and contact element at the top of the lineup. The challenge for the Rays is that Cole rarely walks hitters, so they will need to earn their baserunners rather than wait for mistakes.

New York and Tampa Bay Staffs Among the Best

Both pitching staffs have been excellent this season, which is a big part of why the total sits at only 7. The Yankees own the superior team ERA at 3.21 compared with Tampa Bay's 3.67, while the Rays hold a slight WHIP edge at 1.13 to 1.16. That combination points toward a tight, low-scoring game where every run carries extra weight. Tampa Bay's bullpen depth is a concern with several relievers sidelined, which could matter in the late innings.

  • Tampa Bay leads the AL East at 96-61, six games ahead of the 90-67 Yankees.
  • The teams split Monday's doubleheader, with New York winning 2-0 and Tampa Bay winning 6-1.
  • Monday's two games produced 2 and 7 total runs, with neither going over 7.
  • New York opened at -142 and has moved as high as -158 before settling at -157.
  • The Yankees are drawing 87% of the money and 91% of the tickets.
  • The total opened with the Over favored at -115 and has flipped to the Under at -120.
  • The Over is still drawing 94% of the money and 60% of the tickets despite the move toward the Under.

New York Market Signals

This game features two strong market signals pointing in complementary directions. The side has moved firmly toward the Yankees, confirming support for Cole and the home team. The total has moved hard toward the Under despite overwhelming public backing for the Over. Together, those moves paint a picture of a low-scoring game where New York's pitching controls the action, which is exactly how the opener of Monday's doubleheader played out.

Key Injuries and Things To Know: TB vs NYY

Rays Injury Report

  • Manuel Rodriguez: Reliever, 15-day IL
  • Garrett Cleavinger: Reliever, 15-day IL
  • Gavin Lux: Sidelined
  • Edwin Uceta: Sidelined
  • Jonathan Heasley: Sidelined

Tampa Bay's injuries create real bullpen-depth concerns. With Rodriguez, Cleavinger, Uceta and Heasley unavailable, the Rays have fewer trusted options in the late innings of a close game. That matters in a matchup expected to be decided by a narrow margin, and it adds to the case for New York.

Yankees Injury Report

  • Giancarlo Stanton: Sidelined
  • Trent Grisham: Sidelined
  • Fernando Cruz: Reliever, sidelined
  • Clarke Schmidt: Day-to-day
  • Ryan Weathers: Injured list

New York is missing Stanton and Grisham from the lineup, which takes away some power and depth, while Cruz is out of the bullpen. Even without those pieces, the Yankees still lead this matchup in home run production, and Cole's ability to work deep with minimal walks should reduce the pressure on the relief corps.

Rays vs Yankees Side and Over/Under Picks

Yankees Moneyline Pick

With a projected two-run margin, the moneyline at -157 is the better play than laying -1.5 at +148. Cole's command gives New York the edge in the starting matchup, and the Yankees power bats line up perfectly against a Seymour profile that has allowed 25 home runs. Tampa Bay's thin bullpen adds another layer of support for the home side in a close game. The price has climbed significantly, but the steady move from -142 reflects strong confidence in New York.

Under 7 in New York

The Under 7 at -120 is backed by the pitching matchup, both elite staffs and the strongest market signal in this game. Cole rarely walks hitters, Seymour misses plenty of bats, and both Monday games stayed at or under 7. The reverse line movement against heavy public Over money adds confirmation. The projected 4-2 final comes in comfortably under the total.

  • Side Pick: New York Yankees Moneyline (-157)
  • Total Pick: Under 7 (-120)

Final Score Prediction

Expect Cole to limit Tampa Bay by pounding the strike zone and avoiding walks, forcing the Rays contact attack to work for every run. Seymour should rack up strikeouts, but New York's power bats, led by Rice, are likely to catch at least one of his mistakes. With Tampa Bay's bullpen shorthanded, the Yankees protect a late lead and take the third game of the series.

  • Projected Final Score: Yankees 4, Rays 2
  • Side Result: Yankees moneyline cashes
  • Total Result: Under 7 cashes with 6 total runs

How to Wager On Rays vs Yankees

The Under 7 is the strongest position in this game, supported by both the pitching matchup and the clear reverse line movement. The Yankees moneyline is a secondary play that fits the same script of a low-scoring game controlled by Cole. For bettors looking for more value on New York, the -1.5 at +148 is an option, but with a projected two-run margin, the moneyline offers the more reliable path to a winning ticket.

Pay close attention to price. The Yankees have moved from -142 to -157, and the Under has shifted from -105 to -120, so bettors coming in now are paying more than those who acted early. Shopping across sportsbooks can help you find a cent or two of value, and it is worth checking whether any books are still offering the Under at a cheaper price than -120.

If you want to compare this handicap with model-driven projections, explore our breakdown of the top AI picks platforms. You can also read our full Dimers review to see how its simulations evaluate MLB totals, along with our Oddible review for another tool to uncover value on sides and props before placing your wager on Rays vs Yankees.

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