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Toronto Blue Jays vs Cincinnati Reds Picks and Prediction for Monday September 1 2025

By: Eddie Kline Published 09/01/2025, 01:14 PM ET

The Great American Ball Park will play host to a Monday afternoon MLB interleague clash between the Toronto Blue Jays and the Cincinnati Reds. Be ready for the baseball season with all of our MLB predictions. The Blue Jays (79-58) have split their first 68 road games and hold a three-game lead over New York for the top spot in the AL East Division. On Sunday, leadoff hitter George Springer went 2-for-4 with two runs scored to spark Toronto to an 8-4 home victory versus Milwaukee.

Thirty-six year old righty Chris Bassitt (11-7 4.14 ERA) will take the mound for the Blue Jays in this matchup. In his last start, Bassitt (5.2 IP) gave up two runs and struck out six batters during a 7-5 home loss versus Minnesota.

The Cincinnati Reds have dropped eight of their previous ten games and have fallen four games back of New York in the race for the final NL Wild Card spot. On Sunday, Cincinnati OF T.J. Friedl collected three hits and drove in a pair of runs during a 7-4 home victory versus St. Louis. SP Brady Singer (12-9) allowed three runs in six innings to earn the win for the Reds (69-68), who improved to 37-31 at home.

Cincinnati skipper Terry Francona will turn to hard-throwing righty Hunter Greene (5-4 2.81 ERA) on Monday. Through 77 innings of work, Greene has retired 94 batters by strikes and owns a sparkling 0.97 WHIP.

Blue Jays vs Reds Prediction

Cincinnati SP Chase Burns (elbow) threw a bullpen session on Saturday and is expected to return by the middle of September. Through 137 games, Toronto ranks 3rd in OPS and 7th in runs scored. For the season, Cincinnati ranks 20th in OPS and 13th in runs scored. Take the Reds to win at home. Final Score Prediction, Cincinnati Reds win 5-3.

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