Toronto Blue Jays vs Cincinnati Reds Picks and Predictions for Wednesday, September 3, 2025
Blue Jays Preview
The Toronto Blue Jays complete a three-game series on the road Wednesday versus the Cincinnati Reds. Toronto dropped to 79-59 following Monday’s 5-4 loss to Cincinnati in the opening game of the series. Toronto has lost three of the last four, but the Blue Jays lead the American League East by 2.5 games over both the New York Yankees and the Boston Red Sox. Keep up to date with all the MLB action with our MLB picks.
Bo Bichette is batting .310 with 88 RBI and 176 hits to lead Toronto in both categories. George Springer leads in home runs with 24 and in on-base percentage with .391. Vladimir Guerrero is second in home runs with 21. Toronto is batting .268 with a .429 slugging percentage. On Wednesday, Toronto will send Shane Bieber to the mound. The right-hander is 1-1 with a 2.38 ERA, 15 Ks, and 0 BBs.
Reds Preview
The Cincinnati Reds improved to 70-68 following Monday’s one-run victory over Toronto. Noelvi Marte hit a walk-off two-run single to give Cincinnati the victory on Monday. Cincinnati has won two straight since snapping a five-game losing streak. The Reds trail first place in the National League Central by 14.5 games and are four games behind the third and final wild card spot in the NL.
Elly De La Cruz is batting .272 with 19 home runs, 77 RBI, and 147 hits to lead Cincinnati in each of the four categories. TJ Friedl is the leader in on-base percentage at .368. Cincinnati is batting .247 with a .391 slugging percentage. On Wednesday, the Cincinnati Reds will send Zack Littell to the mound. The right-hander is 9-8 with a 3.63 ERA, 110 Ks, and 27 BBs. 
Blue Jays vs Reds Betting Trends
- Toronto is 2-4 in its last 6
- The OVER has cashed in 8 of the Blue Jays’ last 9
- Cincinnati is 2-5 in its last 7
- The OVER has cashed in 4 of the Reds’ last 6
Blue Jays vs Reds Pick
Cincinnati has lost five of its last seven overall, and the Reds will have a starting pitcher on the mound who has struggled in his last two appearances. Toronto starter Shane Bieber has had two consecutive strong outings, allowing three runs across 11.1 innings with 15 strikeouts and no walks. Cincinnati starter Zack Littell has been hit hard in two consecutive outings, allowing six runs across 10 innings. Final Score Prediction: Toronto Blue Jays win 5-3.
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