Toronto Blue Jays vs New York Yankees Picks and Prediction for Wednesday May 20 2026

By: Kim Smith Published 05/20/2026, 01:10 AM ET
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The Toronto Blue Jays travel to face the New York Yankees on Wednesday May 20, 2026, at Yankee Stadium in Bronx, New York. First pitch is scheduled for 7:05 PM ET with coverage on MLB.TV, MLB Net, and Prime Video. At the time of this writing the odds were not released. Be sure to check out our free MLB picks

Starting Pitchers

Trey Yesavage is expected to start for Toronto in this matchup. The right-hander enters with a 1-1 record, a 1.40 ERA, and a 1.29 WHIP across 19.1 innings pitched. He has allowed 17 hits while recording 21 strikeouts and issuing eight walks without allowing a home run. New York is expected to counter with Cam Schlittler, who enters the contest with a 6-1 record, a 1.35 ERA, and a 0.78 WHIP over 60.0 innings. He has surrendered only 36 hits while striking out 68 batters and walking 11 while allowing just two home runs.

Toronto Trying to Build Momentum on the Road

The Blue Jays enter Wednesday with a 21-26 overall record and an 8-15 road record. Toronto recently lost to New York 7-6 after recently winning over Detroit by scores of 4-1 and 2-1 in 10 innings. The Blue Jays also recently lost to Detroit 3-2 before recently winning over Tampa Bay 5-3 in 10 innings. Toronto has played several close games recently but continues to struggle consistently away from home.

Toronto is batting .243 as a team with 194 runs scored and 384 hits this season. The Blue Jays have hit 44 home runs while posting a .306 on-base percentage and a .373 slugging percentage. On the mound, Toronto owns a 4.03 ERA and a 1.30 WHIP while opponents are batting .250 against the pitching staff. The Blue Jays have issued 147 walks and recorded 421 strikeouts this season.

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One positive for Toronto entering this matchup is the recent starting pitching performance. The Blue Jays starter enters with a 1.40 ERA and has not allowed a home run through 19.1 innings this season. However, Toronto still faces challenges offensively against a New York pitching staff that owns one of the stronger ERA and WHIP combinations in this matchup.

Yankees Looking to Continue Strong Home Play

New York enters this game with a 29-19 overall record and an impressive 15-6 home record. The Yankees recently won over Toronto 7-6 after recently losing to the Mets by scores of 7-6 in 10 innings and 6-3. New York also recently defeated the Mets 5-2 before recently losing to Baltimore 7-0. Despite a few recent setbacks, the Yankees continue to hold one of the stronger records among the teams playing Wednesday.

The Yankees are batting .237 as a team with 244 runs scored and 372 hits this season. New York has hit 71 home runs while posting a .333 on-base percentage and a .433 slugging percentage. On the mound, the Yankees carry a 3.35 ERA and a 1.17 WHIP while limiting opponents to a .221 batting average. The pitching staff has recorded 421 strikeouts and issued 148 walks this season.

One major strength for New York entering this matchup is power production combined with pitching consistency. The Yankees have already hit 71 home runs this season while also holding the stronger ERA, WHIP, and opponent batting average compared to Toronto. New York has also been excellent at home with 15 wins in 21 games at Yankee Stadium.

Toronto Blue Jays vs New York Yankees Picks and Prediction

Toronto Blue Jays vs New York Yankees Pick

  • Pick: New York Yankees Moneyline

New York enters this matchup with stronger overall team numbers and one of the better home records in this matchup. The Yankees also hold the advantage in ERA, WHIP, opponent batting average, home runs, runs scored, on-base percentage, and slugging percentage. While Toronto’s starter has pitched very well in limited innings, the Yankees counter with a starter carrying a 1.35 ERA and a 0.78 WHIP through 60 innings. With New York continuing to produce offensively and pitch consistently at home, the Yankees hold the edge entering Wednesday.

Toronto Blue Jays vs New York Yankees Total Pick

  • Pick: Take the under if the total is set at 8.5

I would lean toward the under because both projected starting pitchers enter with excellent ERA numbers. Toronto’s starter has not allowed a home run this season, while New York’s starter has surrendered only two home runs through 60 innings. The Yankees pitching staff also owns a 3.35 ERA and a .221 opponent batting average, which are strong overall numbers entering this matchup. Even though the previous meeting finished 7-6, the starting pitching setup points toward a more controlled game Wednesday night.

Final Score Prediction: New York Yankees 5 – Toronto Blue Jays 3

This prediction was written before the completion of game play on Tuesday.

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