Washington Nationals vs Chicago Cubs Picks and Prediction for Saturday September 6 2025

By: Eddie Kline Published 09/06/2025, 12:45 AM ET

Nationals Preview

Historic Wrigley Field will play host to a Saturday afternoon MLB clash between the Washington Nationals and the Chicago Cubs. Be ready for the baseball season with all of our MLB predictions. The Nationals (56-84) have dropped seven of their last ten games and are stuck in the NL East Division basement. On Friday, Washington 2B Luis Garcia Jr. homered and drove in three runs during an 11-5 road loss against Chicago.

Twenty-five year old righty Brad Lord (4.34 ERA) will take the mound for the Nationals in this matchup. Washington has dropped Lord’s previous two starts and he has surrendered 13 runs across his last seven plus frames.

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Cubs Preview

The Chicago Cubs have split their previous ten games and are sitting comfortably atop the NL Wild Card standings. During yesterday’s home victory, OF Ian Happ clubbed one of Chicago’s four long balls and scored four times. SS Dansby Swanson contributed a three-run blast for the Cubs (81-60), who improved to 44-26 at home.

The Cubs will counter with thirty-four year old southpaw Matthew Boyd (12-7 2.94 ERA) on Saturday. In 12 home starts this season, Boyd is 10-0 with a 2.12 ERA. The first-time All-Star also ranks 12th in the majors with a sparkling 1.07 WHIP.

Nationals vs Cubs Prediction

Washington SP MacKenzie Gore (shoulder) played catch on Tuesday and hopes to make a start later this month. Through 140 games, Washington ranks 26th in OPS and 24th in runs scored. For the season, Chicago ranks 9th in OPS and 7th in runs scored. Take the under. Final Score Prediction, Chicago Cubs win 5-2.

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