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Washington Nationals vs Chicago Cubs Picks and Predictions for Sunday, September 7, 2025

By: Cameron Ross Published 09/07/2025, 12:45 AM ET

Washington Nationals vs Chicago Cubs Information

The Washington Nationals will finish their road trip in Chicago on Sunday with game three of three against the Chicago Cubs. Sunday brings a matchup in Wrigley Field at 2:20 PM EST between two National League foes. Washington is out of playoff contention, nearly 30 games below .500, following a six-run loss in Game 1 of this set. Chicago is more than 20 games above .500, fighting for playoff seeding, having won three of the last four overall. Stay in the action with our MLB Picks.

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Nationals Preview

The Washington Nationals are one of the worst teams in the National League, well below .500 on the season. Washington has a .243 team batting average this season, having scored 593 runs on 1137 hits. The Washington bullpen has been horrendous this season, with a 5.33 team ERA this year.

Cubs Preview

The Chicago Cubs have a potent offense with a .249 team batting average, having scored 699 runs on 1196 hits. The Chicago power has carried the team this season with 193 home runs and a .429 team slugging percentage. The Chicago pitching has done the job as well this season with a 3.8 team ERA.

Washington Nationals vs Chicago Cubs Pitching Matchup

Andrew Alvarez will take the mound for Washington on Sunday. Alvarez has a small sample size this season, undefeated through one game with a 0.00 ERA through 5 innings pitched overall. Colin Rea will be on the bump for Chicago with ten wins and six losses this season, carrying a 4.30 ERA across 136 innings of work.

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Washington Nationals vs Chicago Cubs Pick

The Chicago Cubs are a far better team in this matchup, and it will show from the opening minutes on Sunday. Chicago is fighting for playoff positioning and will need to get all the wins it can get. It takes Chicago to do the job on both sides of the plate as they get a win and cover at home against Washington on Sunday.

Pick: Cubs -1.5

Secondary: Under

Lean: Seiya Suzuki RBI

Final Score Prediction: Chicago Cubs win and cover 8-1

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