Washington Nationals vs Pittsburgh Pirates Picks and Predictions for Wednesday, April 15, 2026

By: Cameron Ross Published 04/15/2026, 01:20 AM ET
Royals vs Nationals prediction
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Nationals vs Pirates Game Information

The Washington Nationals will stay on the road Wednesday night for game three of four in Pittsburgh against the Pittsburgh Pirates inside PNC Park at 6:40 PM. Washington has eight wins and 9 losses thus far this season, coming into this matchup having won for the last five overall, following a one-run road victory against Pittsburgh in their last outing. The Pittsburgh Pirates stay home on Wednesday with ten wins and seven losses this season, having dropped two of the last three overall. Stay in the news with our MLB Picks.

Nationals  Preview

Offensively, Washington has been solid this season with a .270 team batting average. The Nationals have scored 94 runs on 152 hits this season and have scored 23 runs over their last four wins. CJ Abrams does everything for the Washington offense, leading the team with a .356 batting average, six home runs, and 19 RBI's this year.

Pirates Preview

The Pittsburgh Pirates’ offense has been solid as well this season, with a .250 batting average. The Pirates scored 82 runs on 137 hits. Pittsburgh has a .342 team OBP and a .392 team slugging percentage. The Pittsburgh edge has been phenomenal, with a 3.34 team ERA, but the team has allowed an average of 6 runs per game over its last two losses. O'Neill Cruz has carried the Pittsburgh offense this season with a .328 batting average and sixteen RBI's, both of which lead the team. Brandon Lowe supplies the power to the team with a .268 batting average and a team-leading 7 home runs this season.

Nationals vs Pirates Pitching Matchup

Jake Irvin will take the mound for Washington on Wednesday with one win and one loss this season and a 7.07 ERA across 14 innings of work this season. Carmen Mlodzinski will counter for the Pirates, giving them the edge this season, as he has boasted a 2.51 ERA across 14.1 innings of work.

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Nationals vs Pirates Pick

Both teams have found some success this season, as each is hovering just around .500. Pittsburgh, however, is the better overall team and will do the work in this matchup. Look for the Pirates to win game 3 of this series as they have the better pitcher on the mound and the home fans behind them. Pittsburgh went to do the job as they got their 11th victory of the season following a win against the Washington Nationals.

  • Pick:  Pittsburgh Pirates -181
  • Secondary:  Over 9.5
  • Lean: Oneil Cruz Over 1.5 Bases

Final Score Prediction: Pittsburgh Pirates win 8-4.

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