Chicago Bulls vs Detroit Pistons Picks and Prediction for Wednesday November 12 2025

By: Eddie Kline Published 11/12/2025, 12:50 AM ET

Bulls Preview

Little Caesars Arena will play host to a Wednesday night NBA clash between the Chicago Bulls and the Detroit Pistons. For other NBA action see our NBA Predictions. The Bulls (6-4) have dropped three of their first four road games and rank 12th in the league in offensive efficiency. On Monday, Chicago was outscored by 13 points during the fourth quarter of a 121-117 home loss versus San Antonio.

Kevin Huerter led five Chicago players in double figures with 23 points (8-14 FG), five rebounds, and five assists. Tre Jones and Ayo Dosunmu scored 20 points each on a combined 14-for-27 shooting effort. Matas Buzelis added 15 points and five rebounds for the Bulls. The best sportsbooks are the best way to go when you are betting on the Chicago Bulls.

Pistons Preview

The Detroit Pistons have reeled off seven straight victories and are sitting atop the Eastern Conference standings. The Pistons (9-2) rank second in the league in defensive efficiency and are allowing 112.7 points per contest. On Monday, Detroit rallied from as many as 13 points down to earn a 137-135 overtime victory versus Washington.

All-Star G Cade Cunningham poured in a game-high 46 points (14-45 FG) to go along with 12 rebounds and 11 assists. Daniss Jenkins scored 24 points on 9-for-17 shooting in 34 minutes off the Detroit bench. F/C Jalen Duren contributed 19 points (6-10 FG) and 14 rebounds for the Pistons. Make sure you know about how the fans are looking on social for Detroit with the Thrillz promo code.

Subscribe Now

I authorize Picks And Parlays to send me promotional emails

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Terms & Conditions

Bulls vs Pistons Pick

Detroit will be without F Isaiah Stewart (ankle), Ausar Thompson (ankle), and Tobias Harris (ankle) for this contest. These two teams are pretty evenly matched and the Pistons will be exhausted from Monday’s victory. Take the Bulls to pull off the upset on the road. Final Score Prediction, Chicago Bulls win 121-115. Make sure when you place your Bulls vs Pistons bet you are using the bet365 bonus code.

Never Tried Picks and Parlays? Now Is Your Chance

Get your first daily picks package for ONLY $1 using coupon code BUCK
If the pick loses, we credit your account with 3 Flex Picks
If the pick wins, we still give you 1 Flex Pick on the house
Win or lose, you walk away ahead. One dollar. No catch.

Min. Deposit $5

Cashable No

Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.

Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)

Cashable No

Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET. Call 1-888-789-7777 or visit ccpg.org/chat (CT). Hope is here. GamblingHelplineMA.org or call (800) 327-5050 for 24/7 support (MA). Visit www.mdgamblinghelp.org (MD). Call 1-877-HOPENY or text HOPENY (467369) (NY). 21+ (18+ DC, IA, KY, WV) only. New users only or text HOPENY (467369) (NY). Casino, First online real money wager only. $5 first deposit required. Min $5 wager required for 5 consecutive days. Bonus issued as non-withdrawable Bet Reset tokens. Refund from token issued as nonwithdrawable bonus bet that expire 7 days after receipt. Max refund $200 per day. Restrictions apply, including token expiration. See full terms at fanduel.com/sportsbook. Call 1-877-770-7867 (LA).

Min. Deposit $5

Odds Requirements -500

Cashable No

GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/NH/PR/WY). Void in CAN. Eligibility restrictions apply. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL. 1 per new DraftKings customer. $5+ first-time bet req. Max. $200 issued as non-withdrawable Bonus Bets that expire in 7 days (168 hours). Stake removed from payout. Terms: sportsbook.draftkings.com/promos. Ends 7/19/26 at 11:59 PM ET. Sponsored by DK.