Detroit Pistons vs Boston Celtics Picks and Prediction for Wednesday November 26 2025

By: Eddie Kline Published 11/26/2025, 02:05 AM ET

Pistons Preview

In the first game of a Wednesday NBA on ESPN tripleheader, the Detroit Pistons will square off against the Boston Celtics from TD Garden. For other NBA action see our NBA Predictions. The Pistons (15-2) have reeled off a franchise tying 13 straight victories and are sitting atop the Eastern Conference standings. On Monday, Detroit built a 16-point halftime lead and held on late for a 122-117 road victory against Indiana.

All-Star G Cade Cunningham matched a game-high with 24 points to go along with 11 rebounds and six assists. Caris LeVert scored 19 points on 5-for-9 shooting in 23 minutes off the Detroit bench. C Jalen Duren controlled the interior with 17 points (6-10 FG) and 12 rebounds for the Pistons. The best sportsbooks are the best way to go when you are betting on the Pistons.

Celtics Preview

The Boston Celtics are a game above .500 at home and are tied with Chicago for ninth place in the Eastern Conference standings. The Celtics (9-8) rank seventh in the league in defensive efficiency and are allowing 110 points per contest. On Sunday, Boston outscored Orlando by 18 points during the second quarter and cruised to a 138-129 home victory versus Orlando.

All-Star G Jaylen Brown led all scorers with 35 points on 14-for-26 shooting and grabbed eight rebounds. Anfernee Simons chipped in 23 points and five boards in just 22 minutes off the Boston bench. The Celtics connected on 15-for-33 from long distance and shot a scorching 60 percent overall. Make sure you know about how the fans are looking on prediction markets for the Celtics with the Onyx Odds promo code.

Subscribe Now

I authorize Picks And Parlays to send me promotional emails

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Terms & Conditions

Pistons vs Celtics Pick

Boston C Neemias Queta exited Sunday’s victory with an ankle injury and is listed as day-to-day. The Celtics rank seventh in the league in offensive efficiency to go along with their solid defensive numbers. Take Boston to snap Detroit’s impressive winning streak and with a home victory. Final Score Prediction, Boston Celtics win 118-109. Getting the most out of your bets on Pistons vs Celtics can be done by using the Fanatics Sportsbook promo code.

Never Tried Picks and Parlays? Now Is Your Chance

Get your first daily picks package for ONLY $1 using coupon code BUCK
If the pick loses, we credit your account with 3 Flex Picks
If the pick wins, we still give you 1 Flex Pick on the house
Win or lose, you walk away ahead. One dollar. No catch.

Min. Deposit $5

Cashable No

Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.

Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)

Cashable No

Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET. Call 1-888-789-7777 or visit ccpg.org/chat (CT). Hope is here. GamblingHelplineMA.org or call (800) 327-5050 for 24/7 support (MA). Visit www.mdgamblinghelp.org (MD). Call 1-877-HOPENY or text HOPENY (467369) (NY). 21+ (18+ DC, IA, KY, WV) only. New users only or text HOPENY (467369) (NY). Casino, First online real money wager only. $5 first deposit required. Min $5 wager required for 5 consecutive days. Bonus issued as non-withdrawable Bet Reset tokens. Refund from token issued as nonwithdrawable bonus bet that expire 7 days after receipt. Max refund $200 per day. Restrictions apply, including token expiration. See full terms at fanduel.com/sportsbook. Call 1-877-770-7867 (LA).

Min. Deposit $5

Odds Requirements -500

Cashable No

GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/NH/PR/WY). Void in CAN. Eligibility restrictions apply. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL. 1 per new DraftKings customer. $5+ first-time bet req. Max. $200 issued as non-withdrawable Bonus Bets that expire in 7 days (168 hours). Stake removed from payout. Terms: sportsbook.draftkings.com/promos. Ends 7/19/26 at 11:59 PM ET. Sponsored by DK.