Los Angeles Lakers at Minnesota Timberwolves Picks and Predictions for Wednesday, October 29, 2025
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The Los Angeles Lakers visit the Minnesota Timberwolves at 9:30 PM ET on Wednesday at Target Center in Minneapolis, with national coverage on ESPN. Both teams are 2–2. The Lakers just fell to Portland, while Minnesota is coming off a home loss to Denver. Drive to the basket and dish off for a winning layup with our free NBA Picks.
Los Angeles Lakers Preview
Los Angeles has scored 121.3 points per game on 54.1% shooting, with strong ball movement, averaging 25.0 assists per game. Austin Reaves has carried a heavy playmaking and scoring load with Luka Doncic out, averaging 35.8 points and 8.5 assists per game, and Rui Hachimura adds 16.5 points per game. Deandre Ayton is averaging 15.8 points and 9.3 rebounds per game.
Injuries have hit Los Angeles hard to start the season. Luka Doncic and LeBron James headline a long list that includes Marcus Smart and Jaxson Hayes, and Gabe Vincent, who are all out. The Lakers still have size and excellent shooting from Reaves, and when they keep turnovers down (15.3 per game), the half-court game is strong.
Minnesota Timberwolves Preview
Minnesota averages 114.0 points on 47.3% shooting and averages 44.3 rebounds per game. Julius Randle has started fast at 25.3 points and 6.0 assists per game, giving the Wolves a strong pair of scorers when Anthony Edwards is healthy. With Edwards out injured, Donte DiVincenzo is taking on more of a scoring role (47.4% from three), and Jaden McDaniels adds 13.0 points per game.
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Rudy Gobert anchors the interior at 10.3 rebounds, and his screening frees ballhandlers into open pull-ups. Minnesota’s defense generates 7.7 steals and 5.7 blocks per game, and that has helped their transition game. The key is protecting the paint and staying disciplined at both ends. If the Wolves keep second-chance looks for the Lakers to a minimum, the game will be close throughout.
Los Angeles Lakers at Minnesota Timberwolves Prediction
Los Angeles is shooting well from inside the arc, but Minnesota’s size with Gobert plus Randle’s shot creation gives the Timberwolves an advantage at home. Even with Edwards out, the Wolves still have enough shooting around Randle to prevent double teams, and the defense can bother LA’s shooting. Final Score Prediction: Minnesota Timberwolves win and cover ATS, 111-105
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