Minnesota Timberwolves vs Portland Trailblazers Picks and Predictions for Wednesday, October 22, 2025
Minnesota vs Portland Information
The Minnesota Timberwolves open the 2025 season Wednesday night on the road with a game up north in the Moda Center at 10:00 PM against the Portland Trail Blazers. Minnesota will look to build off last year's success after winning 49 games in the regular season before falling in the conference finals to the Oklahoma City Thunder. The Portland Trail Blazers have somewhat of a new look this season after finishing last year 10 games below .500. Stay in the news with our NBA Picks.
Minnesota Preview
Offensively, Minnesota was solid last season, ranking 13th in the NBA, averaging 114.3 points per game overall. The Minnesota defense was the team's biggest strength, ranking fifth in the league, holding opponents to 109.3 points per game. Anthony Edwards led the Minnesota offense a year ago, averaging 27.6 points per game through 79 games played. Julius Randle was second on the roster, averaging 18.7 points and led the team, dishing out 4.7 assists. Rudy Gobert averaged 12 points and led the team, pulling in 10.9 rebounds per game.
Portland Preview
The Portland Trail Blazers offense ranked 22nd in the league a year ago, scoring just 110.9 points per game overall. Defensively, Portland was a little better, ranking 15th in the league, but gave up 113.9 points per game. Anfernee Simons carried the load for the Portland offense a year ago after 19.3 points per game. Shaedon Sharpe was second on the roster with 18.5 points, and Donovan Clingan averaged 6.5 points to go along with the team-high 7.9 rebounds per game.
Minnesota vs Portland Prediction
Minnesota is a far better team in this matchup and will look to open the year with a bang Wednesday night. The Timberwolves are poised to be one of the better teams in the Western Conference and will start their campaign on the right foot in game one. They should take Minnesota on Wednesday night to secure the win and cover on the road in Portland. Final Score Prediction, Minnesota Timberwolves win and cover 123-108.
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Timberwolves vs Trail Blazers Best Picks
- Minnesota Timberwolves -4.5
- Over 221.5
