Minnesota Timberwolves vs San Antonio Spurs Picks and Prediction for Wednesday May 6 2026
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The Minnesota Timberwolves and San Antonio Spurs continue their Western Conference Semifinal series on Wednesday, May 6, 2026, with Game 2 taking place at Frost Bank Center in San Antonio, Texas. Tip-off is scheduled for 9:30 PM, and the game will air on ESPN. Minnesota enters with a surprising 1-0 series lead after stealing Game 1 on the road. San Antonio remains a heavy favorite for Game 2 at -9.5, while the Timberwolves are listed at +9.5. The total for the matchup is set at 215.5 points. Get ready for the NBA playoff action with our free NBA Picks.
Previous Game Recap
Minnesota secured a narrow 104-102 victory in Game 1, closing the game strong with a 35-point fourth quarter to erase a late deficit. The contest remained tight throughout, with San Antonio holding a slight edge entering the final frame before the Timberwolves rallied late to take home-court advantage away from the Spurs. Both teams struggled at times from deep, but Minnesota capitalized on timely scoring in the closing minutes.
The Timberwolves were led by Julius Randle, who scored 21 points while shooting 8-for-20 from the field and adding 10 rebounds. Anthony Edwards provided a major spark off the bench with 18 points on efficient shooting, while Jaden McDaniels contributed 16 points and Rudy Gobert added 10 rebounds with strong defensive activity. Mike Conley also chipped in 12 points and six assists as Minnesota shot 46 percent from the field.
San Antonio received strong production from several key contributors despite the loss. Stephon Castle scored 17 points while adding five assists, and Victor Wembanyama posted 11 points, 15 rebounds, and 12 blocks in an impactful defensive performance. Devin Vassell finished with 14 points, while De’Aaron Fox contributed 10 points and six assists. Dylan Harper added 18 points off the bench as the Spurs narrowly fell short after shooting 45 percent from the field. 
Timberwolves Carry Momentum Into Game 2
Minnesota enters this matchup with a 49-33 overall record and a 23-18 record on the road. The Timberwolves have recently won over San Antonio, recently won over Denver twice, recently lost to Denver on the road, and recently won over Denver again in another strong playoff performance. Their Game 1 victory gives them confidence heading into another difficult road environment.
The Timberwolves averaged 118.0 points per game during the season while allowing 106.7 points against. Minnesota also averaged 44.1 rebounds and 26.1 assists per game while shooting 48 percent from the field. Defensively, they produced 8.7 steals and 5.8 blocks per game, showing balance on both ends of the floor.
One major strength for Minnesota is their defensive consistency. Allowing only 106.7 points per game against a Spurs offense that averaged nearly 120 points per contest is significant. The Timberwolves also showed in Game 1 that they can stay composed late in close games, which becomes especially important in playoff road environments.
Spurs Look to Respond at Home
San Antonio enters Game 2 with a dominant 62-20 overall record and an excellent 32-8 home record. The Spurs recently lost to Minnesota in Game 1 but had previously recently won over Portland three straight times before the series shifted to the second round. Despite the opening loss, San Antonio remains in a strong position with another home game ahead.
The Spurs averaged 119.8 points per game during the regular season while allowing just 100.7 points against. They also averaged 47.0 rebounds and 28.1 assists per game while shooting 48 percent from the field. Defensively, San Antonio added 7.5 steals and 5.5 blocks per game, making them one of the more complete teams statistically.
The biggest advantage for San Antonio is overall balance. The Spurs averaged more points, rebounds, and assists than Minnesota during the season while also allowing fewer points defensively. Their ability to create offense from multiple players was still visible in Game 1 despite the loss, and their strong home record suggests they are capable of responding quickly.
Minnesota Timberwolves vs San Antonio Spurs Picks and Prediction
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Bruce Marshall | +9,181.00 |
| 2 |  Sean Higgs | +4,349.00 |
| 3 |  Bryan Power | +3,755.00 |
| 4 |  Pro Sports Picks | +3,426.00 |
| 5 |  Steve Seagrave | +3,226.00 |
Side Pick: San Antonio Spurs -9.5
Even after dropping Game 1, San Antonio still holds several statistical advantages entering this matchup. The Spurs averaged nearly two more points per game offensively while allowing six fewer points defensively over the season. They also dominated at home with a 32-8 record and were competitive throughout Game 1 despite an inconsistent shooting night from deep. Minnesota has been impressive lately, but asking the Timberwolves to win consecutive games on the road against a 62-win team is difficult. San Antonio looks positioned to respond with a stronger overall effort in Game 2.
Total Pick: Under 215.5
Game 1 finished with a combined 206 points, and both teams showed strong defensive stretches throughout the night. Minnesota allows only 106.7 points per game, while San Antonio gives up just 100.7 points per contest. The Timberwolves also slowed the pace effectively in the opener, and playoff basketball often becomes more physical and defensive as series progress. With both teams capable defensively and Game 1 already staying under this number comfortably, the under is the preferred play again.
Final Score Prediction: San Antonio Spurs 111 – Minnesota Timberwolves 100
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