NBA Parlay for Wednesday 12/10/25

By: Kim Smith Published 12/10/2025, 03:15 AM ET

Wednesday brings two NBA Cup group-stage matchups featuring elite Western Conference teams against opponents trying to break through. Oklahoma City continues its historic run on top of the league, while the Lakers look to protect home court against a rising Spurs squad. Both games offer clear statistical edges, making for a strong 2-leg parlay.

Check out our parlays, as well as all of our NBA picks.

NBA Parlay

  • Phoenix Suns vs Oklahoma City Thunder – Thunder -14.5 (-112)
  • San Antonio Spurs vs Los Angeles Lakers – Lakers -5.5 (-110)

Leg 1 – Phoenix Suns vs Oklahoma City Thunder

The Thunder enter this matchup with a league-best 23–1 record, riding a 15-game winning streak, and still undefeated at home at 11–0. Oklahoma City owns massive advantages in efficiency, depth, pace, and defense, and the Suns come in short-handed at the worst possible time.

Phoenix is dealing with key injuries:

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  • Devin Booker – GTD

  • Jalen Green – OUT

  • Isaiah Livers – OUT

  • Koby Brea – GTD

Without Booker at full strength, the Suns' scoring ceiling drops significantly. They’re already a middling defensive team, allowing 113.5 PPG, and they recently lost to OKC on November 28th 123–119 when OKC wasn’t even at peak form.

Since then, OKC has redlined:

  • Last 5 games: scored 131, 132, 124, 123, 123

  • Season averages: 123.0 PPG on 50% FG

  • Defensive average: just 106.9 allowed

Shai Gilgeous-Alexander is on an MVP-level tear at 32.8 PPG, and the Thunder continue to get elite contributions across the roster.

Phoenix can score, but they cannot defend at a level capable of slowing OKC’s relentless tempo. The ESPN predictor gives OKC 89% win probability, one of the highest of the night.

With OKC undefeated at home and crushing spreads, the Thunder -14.5 is the logical side.

Be sure to check out the full Phoenix Suns vs Oklahoma City Thunder pick.

Leg 2 – San Antonio Spurs vs Los Angeles Lakers

This matchup features two strong teams, but the Lakers hold the clear advantage due to health, star power, and home success. Los Angeles is 17–6, including 7–3 at home, and remains one of the best offensive teams in the league.

Luka DončiΔ‡ continues his MVP-level campaign at 35.0 PPG, and the Lakers’ offense is hitting stride again after a tough back-to-back schedule. While the Spurs have been good, the loss of Victor Wembanyama (OUT) plays a massive role in the handicap.

San Antonio’s defense already struggles without him:

  • 115.3 points allowed per game

  • 44.6 opponent rebounds

  • Defensive rim protection collapses without Wemby

The Lakers, meanwhile:

  • Score 118.3 PPG

  • Shoot 51% from the field – one of the best marks in the NBA

  • Have won 8 of their last 10

Recent form also favors L.A.:

  • Beat Philadelphia on the road

  • Narrow loss to Boston but competitive

  • Beat Toronto

  • Competitive vs Phoenix before late fade

The Spurs are 7–5 on the road, but many of those wins came against weaker defenses. Against top contenders, their flaws show.

The ESPN predictor gives the Lakers a 67.2% chance of winning, backed by their superior roster, efficiency, and home-court strength.

With DončiΔ‡ leading the hottest stretch of his season and San Antonio missing their best interior player, the Lakers -5.5 is the sharper play.

Be sure to check out the full San Antonio Spurs vs Los Angeles Lakers pick.

Final Parlay Thoughts

Both picks lean into clear, quantifiable advantages:

  • OKC is the best team in the NBA, playing at home, and nearly unstoppable offensively.

  • The Lakers are healthier, deeper, and far more polished than the Spurs without Wembanyama.

If the games play to their statistical profiles, this Wednesday parlay offers high-value potential.

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