Chicago Blackhawks vs. St. Louis Blues Picks and Prediction for Wednesday, October 15, 2025

By: Jake Allman Published 10/15/2025, 12:15 AM ET

The Central Division matchup between the Chicago Blackhawks and the St. Louis Blues drops the puck on Wednesday at 9:30 PM ET at Enterprise Center, airing on TNT and HBO Max. St. Louis enters at 2-1-0 after a convincing 5-2 win over Vancouver, while Chicago sits at 1-2-1 following a home victory against Utah. The Blues are listed as favorites. Don’t get iced out — skate with our expert NHL predictions.

Blackhawks Preview

Chicago’s attack has been slightly above average, with a goals-for of 2.5 per game. Teuvo Teravainen is leading the way at five points through four contests. Connor Bedard continues to drive the attack with two goals, including one on the power play. The Blackhawks have struggled to maintain offensive pressure, however, generating just 19.8 shots per game — one of the lowest marks in the league. That lack of puck possession has forced the goaltenders to work harder. Despite that, Spencer Knight has been solid with a .920 save percentage and 2.35 goals-against average. Special teams remain a concern, as Chicago’s power play is converting at just 15.4%, while the penalty kill is at 80%.

Blues Preview

St. Louis, coming off a strong road win in Vancouver, has looked strong across all lines. Jake Neighbours leads the team with three goals, and the Blues are averaging 3.0 goals per game on nearly 30 shots. The power play has been an early bright spot, converting 22.2% of the time, which gives them an edge over Chicago. Jordan Binnington and Joel Hofer have split starts effectively, with Hofer posting a .931 save percentage and 2.00 GAA. St. Louis is limiting opponents to 26.3 shots per game, a strong indicator of defensive toughness and puck possession on attack.

Blackhawks vs Blues Pick

Injuries play a small role here. Chicago remains without Landon Slaggert and Joey Anderson, while the Blues are missing a few forwards, including Milan Lucic and Alexey Toropchenko. That said, St. Louis’ top lines remain intact, and the forecheck has been especially strong through the first three games. The Blues’ ability to generate scoring behind Neighbours and Jordan Kyrou gives them an advantage against the still-developing Blackhawks.

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St. Louis is more effective on the power play and penalty kill, steadier in goal, and able to control possession. Chicago’s young forwards have talent, but shots on goal have been an issue, and the reliance on Knight and Bedard gives the Blackhawks fewer options. Expect St. Louis to dictate the pace and keep Chicago on its heels.

Final Prediction: St. Louis Blues 4, Chicago Blackhawks 2

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